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Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas.
Fennell L, Dumenil T, Wockner L, Hartel G, Nones K, Bond C, Borowsky J, Liu C, McKeone D, Bowdler L, Montgomery G, Klein K, Hoffmann I, Patch AM, Kazakoff S, Pearson J, Waddell N, Wirapati P, Lochhead P, Imamura Y, Ogino S, Shao R, Tejpar S, Leggett B, Whitehall V. Fennell L, et al. Among authors: bowdler l. Cell Mol Gastroenterol Hepatol. 2019;8(2):269-290. doi: 10.1016/j.jcmgh.2019.04.002. Epub 2019 Apr 5. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30954552 Free PMC article.
Identification of 55,000 Replicated DNA Methylation QTL.
McRae AF, Marioni RE, Shah S, Yang J, Powell JE, Harris SE, Gibson J, Henders AK, Bowdler L, Painter JN, Murphy L, Martin NG, Starr JM, Wray NR, Deary IJ, Visscher PM, Montgomery GW. McRae AF, et al. Among authors: bowdler l. Sci Rep. 2018 Dec 4;8(1):17605. doi: 10.1038/s41598-018-35871-w. Sci Rep. 2018. PMID: 30514905 Free PMC article.
Independent Replication and Meta-Analysis for Endometriosis Risk Loci.
Sapkota Y, Fassbender A, Bowdler L, Fung JN, Peterse D, O D, Montgomery GW, Nyholt DR, D'Hooghe TM. Sapkota Y, et al. Among authors: bowdler l. Twin Res Hum Genet. 2015 Oct;18(5):518-25. doi: 10.1017/thg.2015.61. Epub 2015 Sep 4. Twin Res Hum Genet. 2015. PMID: 26337243
Endometrial vezatin and its association with endometriosis risk.
Holdsworth-Carson SJ, Fung JN, Luong HT, Sapkota Y, Bowdler LM, Wallace L, Teh WT, Powell JE, Girling JE, Healey M, Montgomery GW, Rogers PA. Holdsworth-Carson SJ, et al. Among authors: bowdler lm. Hum Reprod. 2016 May;31(5):999-1013. doi: 10.1093/humrep/dew047. Epub 2016 Mar 22. Hum Reprod. 2016. PMID: 27005890
Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339.
Powell JE, Fung JN, Shakhbazov K, Sapkota Y, Cloonan N, Hemani G, Hillman KM, Kaufmann S, Luong HT, Bowdler L, Painter JN, Holdsworth-Carson SJ, Visscher PM, Dinger ME, Healey M, Nyholt DR, French JD, Edwards SL, Rogers PA, Montgomery GW. Powell JE, et al. Among authors: bowdler l. Hum Mol Genet. 2016 Nov 15;25(22):5046-5058. doi: 10.1093/hmg/ddw320. Hum Mol Genet. 2016. PMID: 28171565
Germline variants are associated with increased primary melanoma tumor thickness at diagnosis.
Mangantig E, MacGregor S, Iles MM, Scolyer RA, Cust AE, Hayward NK, Montgomery GW, Duffy DL, Thompson JF, Henders A, Bowdler L, Rowe C, Cadby G, Mann GJ, Whiteman DC, Long GV, Ward SV, Khosrotehrani K, Barrett JH, Law MH. Mangantig E, et al. Among authors: bowdler l. Hum Mol Genet. 2021 Jan 6;29(21):3578-3587. doi: 10.1093/hmg/ddaa222. Hum Mol Genet. 2021. PMID: 33410475 Free PMC article.
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