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XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia.
Chen G, Ribeiro CMP, Sun L, Okuda K, Kato T, Gilmore RC, Martino MB, Dang H, Abzhanova A, Lin JM, Hull-Ryde EA, Volmer AS, Randell SH, Livraghi-Butrico A, Deng Y, Scherer PE, Stripp BR, O'Neal WK, Boucher RC. Chen G, et al. Among authors: scherer pe. Am J Respir Crit Care Med. 2019 Jul 15;200(2):220-234. doi: 10.1164/rccm.201810-1972OC. Am J Respir Crit Care Med. 2019. PMID: 30973754 Free PMC article.
The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism.
Deng Y, Wang ZV, Tao C, Gao N, Holland WL, Ferdous A, Repa JJ, Liang G, Ye J, Lehrman MA, Hill JA, Horton JD, Scherer PE. Deng Y, et al. Among authors: scherer pe. J Clin Invest. 2013 Jan;123(1):455-68. doi: 10.1172/JCI62819. Epub 2012 Dec 21. J Clin Invest. 2013. PMID: 23257357 Free PMC article.
PPARγ in vagal neurons regulates high-fat diet induced thermogenesis.
Liu C, Bookout AL, Lee S, Sun K, Jia L, Lee C, Udit S, Deng Y, Scherer PE, Mangelsdorf DJ, Gautron L, Elmquist JK. Liu C, et al. Among authors: scherer pe. Cell Metab. 2014 Apr 1;19(4):722-30. doi: 10.1016/j.cmet.2014.01.021. Cell Metab. 2014. PMID: 24703703 Free PMC article.
Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.
Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW, Jia L, Fujikawa T, Kohno D, Scott MM, Lee S, Lee CE, Sun K, Chang Y, Scherer PE, Elmquist JK. Williams KW, et al. Among authors: scherer pe. Cell Metab. 2014 Sep 2;20(3):471-82. doi: 10.1016/j.cmet.2014.06.002. Epub 2014 Jul 10. Cell Metab. 2014. PMID: 25017942 Free PMC article.
Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.
Deng Y, Wang ZV, Gordillo R, Zhu Y, Ali A, Zhang C, Wang X, Shao M, Zhang Z, Iyengar P, Gupta RK, Horton JD, Hill JA, Scherer PE. Deng Y, et al. Among authors: scherer pe. Mol Metab. 2018 May;11:1-17. doi: 10.1016/j.molmet.2018.02.013. Epub 2018 Mar 2. Mol Metab. 2018. PMID: 29551634 Free PMC article.
Spliced X-box Binding Protein 1 Stimulates Adaptive Growth Through Activation of mTOR.
Wang X, Deng Y, Zhang G, Li C, Ding G, May HI, Tran DH, Luo X, Jiang DS, Li DL, Wei X, Xu L, Ferdous A, Gillette TG, Scherer PE, Jiang X, Wang ZV. Wang X, et al. Among authors: scherer pe. Circulation. 2019 Aug 13;140(7):566-579. doi: 10.1161/CIRCULATIONAHA.118.038924. Epub 2019 Jun 10. Circulation. 2019. PMID: 31177839 Free PMC article.
517 results