Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
Sung KW, Kirby M, McDonald MP, Lovinger DM, Delpire E.
Sung KW, et al. Among authors: delpire e.
J Neurosci. 2000 Oct 15;20(20):7531-8. doi: 10.1523/JNEUROSCI.20-20-07531.2000.
J Neurosci. 2000.
PMID: 11027211
Free PMC article.
In contrast to control neurons, little or no net current was observed at the resting membrane potential in homozygote NKCC1 mutant DRG neurons. E(GABA) was significantly more negative, demonstrating the absence of Cl(-) accumulation in these cells. Application of bumetanid …
In contrast to control neurons, little or no net current was observed at the resting membrane potential in homozygote NKCC1 mutant DRG neuro …