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A Prospective, Single-Arm, Multicenter Trial of Catheter-Directed Mechanical Thrombectomy for Intermediate-Risk Acute Pulmonary Embolism: The FLARE Study.
Tu T, Toma C, Tapson VF, Adams C, Jaber WA, Silver M, Khandhar S, Amin R, Weinberg M, Engelhardt T, Hunter M, Holmes D, Hoots G, Hamdalla H, Maholic RL, Lilly SM, Ouriel K, Rosenfield K; FLARE Investigators. Tu T, et al. Among authors: maholic rl. JACC Cardiovasc Interv. 2019 May 13;12(9):859-869. doi: 10.1016/j.jcin.2018.12.022. JACC Cardiovasc Interv. 2019. PMID: 31072507 Free article. Clinical Trial.
Catheter-directed interventions compared with systemic thrombolysis achieve improved ventricular function recovery at a potentially lower complication rate for acute pulmonary embolism.
Avgerinos ED, Abou Ali AN, Liang NL, Rivera-Lebron B, Toma C, Maholic R, Makaroun MS, Chaer RA. Avgerinos ED, et al. J Vasc Surg Venous Lymphat Disord. 2018 Jul;6(4):425-432. doi: 10.1016/j.jvsv.2017.12.058. Epub 2018 Mar 31. J Vasc Surg Venous Lymphat Disord. 2018. PMID: 29615372 Free PMC article.
A Randomized Trial of the Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Intermediate-Risk Pulmonary Embolism: The OPTALYSE PE Trial.
Tapson VF, Sterling K, Jones N, Elder M, Tripathy U, Brower J, Maholic RL, Ross CB, Natarajan K, Fong P, Greenspon L, Tamaddon H, Piracha AR, Engelhardt T, Katopodis J, Marques V, Sharp ASP, Piazza G, Goldhaber SZ. Tapson VF, et al. Among authors: maholic rl. JACC Cardiovasc Interv. 2018 Jul 23;11(14):1401-1410. doi: 10.1016/j.jcin.2018.04.008. JACC Cardiovasc Interv. 2018. PMID: 30025734 Free article. Clinical Trial.
Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE).
Sterling KM, Goldhaber SZ, Sharp ASP, Kucher N, Jones N, Maholic R, Meneveau N, Zlotnick D, Sayfo S, Konstantinides SV, Piazza G. Sterling KM, et al. Circ Cardiovasc Interv. 2024 Mar;17(3):e013448. doi: 10.1161/CIRCINTERVENTIONS.123.013448. Epub 2024 Jan 24. Circ Cardiovasc Interv. 2024. PMID: 38264938 Free PMC article.