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Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge.
Stapleton NM, Brinkhaus M, Armour KL, Bentlage AEH, de Taeye SW, Temming AR, Mok JY, Brasser G, Maas M, van Esch WJE, Clark MR, Williamson LM, van der Schoot CE, Vidarsson G. Stapleton NM, et al. Among authors: clark mr. Sci Rep. 2019 May 14;9(1):7363. doi: 10.1038/s41598-019-40731-2. Sci Rep. 2019. PMID: 31089170 Free PMC article.
517 results