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The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.
Andrabi R, Pallesen J, Allen JD, Song G, Zhang J, de Val N, Gegg G, Porter K, Su CY, Pauthner M, Newman A, Bouton-Verville H, Garces F, Wilson IA, Crispin M, Hahn BH, Haynes BF, Verkoczy L, Ward AB, Burton DR. Andrabi R, et al. Among authors: garces f. Cell Rep. 2019 May 21;27(8):2426-2441.e6. doi: 10.1016/j.celrep.2019.04.082. Cell Rep. 2019. PMID: 31116986 Free PMC article.
Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, Cottrell CA, Torres JL, Vavourakis CD, van Gils MJ, LaBranche C, Montefiori DC, Desaire H, Crispin M, Klasse PJ, Lee KK, Moore JP, Ward AB, Wilson IA, Sanders RW. Torrents de la Peña A, et al. Among authors: garces f. Cell Rep. 2017 Aug 22;20(8):1805-1817. doi: 10.1016/j.celrep.2017.07.077. Cell Rep. 2017. PMID: 28834745 Free PMC article.
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
Sliepen K, Han BW, Bontjer I, Mooij P, Garces F, Behrens AJ, Rantalainen K, Kumar S, Sarkar A, Brouwer PJM, Hua Y, Tolazzi M, Schermer E, Torres JL, Ozorowski G, van der Woude P, de la Peña AT, van Breemen MJ, Camacho-Sánchez JM, Burger JA, Medina-Ramírez M, González N, Alcami J, LaBranche C, Scarlatti G, van Gils MJ, Crispin M, Montefiori DC, Ward AB, Koopman G, Moore JP, Shattock RJ, Bogers WM, Wilson IA, Sanders RW. Sliepen K, et al. Among authors: garces f. Nat Commun. 2019 May 29;10(1):2355. doi: 10.1038/s41467-019-10262-5. Nat Commun. 2019. PMID: 31142746 Free PMC article.
Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Kong L, Torrents de la Peña A, Deller MC, Garces F, Sliepen K, Hua Y, Stanfield RL, Sanders RW, Wilson IA. Kong L, et al. Among authors: garces f. Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2099-108. doi: 10.1107/S1399004715013917. Epub 2015 Sep 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26457433 Free PMC article.
Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang CH, Ramos A, Bian CB, Wickramasinghe L, Kong L, Eren K, Wu CY, Wong CH; IAVI Protocol C Investigators & The IAVI African HIV Research Network; Kosakovsky Pond SL, Wilson IA, Burton DR, Poignard P. MacLeod DT, et al. Among authors: garces f. Immunity. 2016 May 17;44(5):1215-26. doi: 10.1016/j.immuni.2016.04.016. Immunity. 2016. PMID: 27192579 Free PMC article.
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