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Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. Ardain A, et al. Among authors: kaushal d. Nature. 2019 Jun;570(7762):528-532. doi: 10.1038/s41586-019-1276-2. Epub 2019 Jun 5. Nature. 2019. PMID: 31168092 Free PMC article.
CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.
Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA. Slight SR, et al. Among authors: kaushal d. J Clin Invest. 2013 Feb;123(2):712-26. doi: 10.1172/JCI65728. Epub 2013 Jan 2. J Clin Invest. 2013. PMID: 23281399 Free PMC article.
S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis.
Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Cumming B, Kasprowicz VO, Steyn AJ, Babu S, Kaushal D, Zúñiga J, Vogl T, Rangel-Moreno J, Khader SA. Gopal R, et al. Among authors: kaushal d. Am J Respir Crit Care Med. 2013 Nov 1;188(9):1137-46. doi: 10.1164/rccm.201304-0803OC. Am J Respir Crit Care Med. 2013. PMID: 24047412 Free PMC article.
Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection.
Gopal R, Monin L, Slight S, Uche U, Blanchard E, Fallert Junecko BA, Ramos-Payan R, Stallings CL, Reinhart TA, Kolls JK, Kaushal D, Nagarajan U, Rangel-Moreno J, Khader SA. Gopal R, et al. Among authors: kaushal d. PLoS Pathog. 2014 May 15;10(5):e1004099. doi: 10.1371/journal.ppat.1004099. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24831696 Free PMC article.
LAG3 expression in active Mycobacterium tuberculosis infections.
Phillips BL, Mehra S, Ahsan MH, Selman M, Khader SA, Kaushal D. Phillips BL, et al. Among authors: kaushal d. Am J Pathol. 2015 Mar;185(3):820-33. doi: 10.1016/j.ajpath.2014.11.003. Epub 2014 Dec 27. Am J Pathol. 2015. PMID: 25549835 Free PMC article.
The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence.
Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, Golden NA, Gautam US, Johnson AM, Alvarez X, Russell-Lodrigue KE, Doyle LA, Roy CJ, Niu T, Blanchard JL, Khader SA, Lackner AA, Sherman DR, Kaushal D. Mehra S, et al. Among authors: kaushal d. Am J Respir Crit Care Med. 2015 May 15;191(10):1185-96. doi: 10.1164/rccm.201408-1502OC. Am J Respir Crit Care Med. 2015. PMID: 25730547 Free PMC article.
Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.
Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, Rengarajan J, Lackner AA, Khader SA, Mehra S. Kaushal D, et al. Nat Commun. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533. Nat Commun. 2015. PMID: 26460802 Free PMC article.
CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.
Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR Jr, Kaushal D. Foreman TW, et al. Among authors: kaushal d. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5636-44. doi: 10.1073/pnas.1611987113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601645 Free PMC article.
283 results