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Complement C3 inhibition by compstatin Cp40 prevents intra- and extravascular hemolysis of red blood cells.
Baas I, Delvasto-Nuñez L, Ligthart P, Brouwer C, Folman C, Reis ES, Ricklin D, Lambris JD, Wouters D, de Haas M, Jongerius I, Zeerleder SS. Baas I, et al. Among authors: delvasto nunez l. Haematologica. 2020 Jan 31;105(2):e57-e60. doi: 10.3324/haematol.2019.216028. Print 2020. Haematologica. 2020. PMID: 31171642 Free PMC article. No abstract available.
It takes two to thrombosis: Hemolysis and complement.
Delvasto-Nuñez L, Jongerius I, Zeerleder S. Delvasto-Nuñez L, et al. Blood Rev. 2021 Nov;50:100834. doi: 10.1016/j.blre.2021.100834. Epub 2021 Apr 30. Blood Rev. 2021. PMID: 33985796 Free article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 34171935
C1-inhibitor treatment in patients with severe complement-mediated autoimmune hemolytic anemia.
de Boer ECW, Jalink M, Delvasto-Nuñez L, Meulenbroek EM, Baas I, Janssen SR, Folman CC, Gelderman KA, Wouters D, Engel MD, de Haas M, Kersten MJ, Jongerius I, Zeerleder S, Vos JMI. de Boer ECW, et al. Among authors: delvasto nunez l. Blood Adv. 2023 Jul 11;7(13):3128-3139. doi: 10.1182/bloodadvances.2022009402. Blood Adv. 2023. PMID: 36920779 Free PMC article. Clinical Trial.