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Extended-Duration MK-8591-Eluting Implant as a Candidate for HIV Treatment and Prevention.
Barrett SE, Teller RS, Forster SP, Li L, Mackey MA, Skomski D, Yang Z, Fillgrove KL, Doto GJ, Wood SL, Lebron J, Grobler JA, Sanchez RI, Liu Z, Lu B, Niu T, Sun L, Gindy ME. Barrett SE, et al. Antimicrob Agents Chemother. 2018 Sep 24;62(10):e01058-18. doi: 10.1128/AAC.01058-18. Print 2018 Oct. Antimicrob Agents Chemother. 2018. PMID: 30012772 Free PMC article.
A phase 1, open-label study to evaluate the drug interaction between islatravir (MK-8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females.
Ankrom W, Jackson Rudd D, Zhang S, Fillgrove KL, Gravesande KN, Matthews RP, Brimhall D, Stoch SA, Iwamoto MN. Ankrom W, et al. Among authors: fillgrove kl. J Int AIDS Soc. 2021 Dec;24(12):e25858. doi: 10.1002/jia2.25858. J Int AIDS Soc. 2021. PMID: 34935295 Free PMC article. Clinical Trial.
Characterisation of the absorption, distribution, metabolism, excretion and mass balance of doravirine, a non-nucleoside reverse transcriptase inhibitor in humans.
Sanchez RI, Fillgrove KL, Yee KL, Liang Y, Lu B, Tatavarti A, Liu R, Anderson MS, Behm MO, Fan L, Li Y, Butterton JR, Iwamoto M, Khalilieh SG. Sanchez RI, et al. Xenobiotica. 2019 Apr;49(4):422-432. doi: 10.1080/00498254.2018.1451667. Epub 2018 Mar 28. Xenobiotica. 2019. PMID: 29557716 Clinical Trial.
Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK-8591 (4'-Ethynyl-2-fluoro-2'-deoxyadenosine).
Alexandre FR, Rahali R, Rahali H, Guillon S, Convard T, Fillgrove K, Lai MT, Meillon JC, Xu M, Small J, Dousson CB, Raheem IT. Alexandre FR, et al. Among authors: fillgrove k. J Med Chem. 2018 Oct 25;61(20):9218-9228. doi: 10.1021/acs.jmedchem.8b00141. Epub 2018 Oct 12. J Med Chem. 2018. PMID: 30265808
30 results