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Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning.
Makielski KM, Donnelly AJ, Khammanivong A, Scott MC, Ortiz AR, Galvan DC, Tomiyasu H, Amaya C, Ward KA, Montoya A, Garbe JR, Mills LJ, Cutter GR, Fenger JM, Kisseberth WC, O'Brien TD, Weigel BJ, Spector LG, Bryan BA, Subramanian S, Modiano JF. Makielski KM, et al. Among authors: mills lj. Lab Invest. 2021 Dec;101(12):1585-1596. doi: 10.1038/s41374-021-00655-w. Epub 2021 Sep 6. Lab Invest. 2021. PMID: 34489559 Free article.
Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma.
Makielski KM, Sarver AL, Henson MS, Stuebner KM, Borgatti A, Suksanpaisan L, Preusser C, Tabaran AF, Cornax I, O'Sullivan MG, Chehadeh A, Groschen D, Bergsrud K, Pracht S, Winter A, Mills LJ, Schwabenlander MD, Wolfe M, Farrar MA, Cutter GR, Koopmeiners JS, Russell SJ, Modiano JF, Naik S. Makielski KM, et al. Among authors: mills lj. Mol Ther Oncolytics. 2023 Oct 14;31:100736. doi: 10.1016/j.omto.2023.100736. eCollection 2023 Dec 19. Mol Ther Oncolytics. 2023. PMID: 37965295 Free PMC article.
Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells.
Nelson CE, Mills LJ, McCurtain JL, Thompson EA, Seelig DM, Bhela S, Quarnstrom CF, Fife BT, Vezys V. Nelson CE, et al. Among authors: mills lj. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2640-2645. doi: 10.1073/pnas.1810326116. Epub 2019 Jan 24. Proc Natl Acad Sci U S A. 2019. PMID: 30679280 Free PMC article.
Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm.
Magli A, Baik J, Mills LJ, Kwak IY, Dillon BS, Mondragon Gonzalez R, Stafford DA, Swanson SA, Stewart R, Thomson JA, Garry DJ, Dynlacht BD, Perlingeiro RCR. Magli A, et al. Among authors: mills lj. PLoS Biol. 2019 Feb 26;17(2):e3000153. doi: 10.1371/journal.pbio.3000153. eCollection 2019 Feb. PLoS Biol. 2019. PMID: 30807574 Free PMC article.
Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma.
Smeester BA, Draper GM, Slipek NJ, Larsson AT, Stratton N, Pomeroy EJ, Becklin KL, Yamamoto K, Williams KB, Laoharawee K, Peterson JJ, Abrahante JE, Rathe SK, Mills LJ, Crosby MR, Hudson WA, Rahrmann EP, Largaespada DA, Moriarity BS. Smeester BA, et al. Among authors: mills lj. Mol Cancer Ther. 2020 Dec;19(12):2528-2541. doi: 10.1158/1535-7163.MCT-20-0369. Epub 2020 Sep 30. Mol Cancer Ther. 2020. PMID: 32999043 Free PMC article.
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma.
Smeester BA, Slipek NJ, Pomeroy EJ, Laoharawee K, Osum SH, Larsson AT, Williams KB, Stratton N, Yamamoto K, Peterson JJ, Rathe SK, Mills LJ, Hudson WA, Crosby MR, Wang M, Rahrmann EP, Moriarity BS, Largaespada DA. Smeester BA, et al. Among authors: mills lj. Bone. 2020 Jul;136:115353. doi: 10.1016/j.bone.2020.115353. Epub 2020 Apr 3. Bone. 2020. PMID: 32251854
80 results