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TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals.
Jiménez JM, Salazar ML, Arancibia S, Villar J, Salazar F, Brown GD, Lavelle EC, Martínez-Pomares L, Ortiz-Quintero J, Lavandero S, Manubens A, Becker MI. Jiménez JM, et al. Among authors: lavelle ec. Front Immunol. 2019 May 31;10:1136. doi: 10.3389/fimmu.2019.01136. eCollection 2019. Front Immunol. 2019. PMID: 31214162 Free PMC article.
Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.
Jarnicki AG, Conroy H, Brereton C, Donnelly G, Toomey D, Walsh K, Sweeney C, Leavy O, Fletcher J, Lavelle EC, Dunne P, Mills KH. Jarnicki AG, et al. Among authors: lavelle ec. J Immunol. 2008 Mar 15;180(6):3797-806. doi: 10.4049/jimmunol.180.6.3797. J Immunol. 2008. PMID: 18322186
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
McNeela EA, Burke A, Neill DR, Baxter C, Fernandes VE, Ferreira D, Smeaton S, El-Rachkidy R, McLoughlin RM, Mori A, Moran B, Fitzgerald KA, Tschopp J, Pétrilli V, Andrew PW, Kadioglu A, Lavelle EC. McNeela EA, et al. Among authors: lavelle ec. PLoS Pathog. 2010 Nov 11;6(11):e1001191. doi: 10.1371/journal.ppat.1001191. PLoS Pathog. 2010. PMID: 21085613 Free PMC article.
136 results