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TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.
Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kløverpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM. Wong EB, et al. Commun Biol. 2019 Jun 5;2:203. doi: 10.1038/s42003-019-0442-2. eCollection 2019. Commun Biol. 2019. PMID: 31231693 Free PMC article.
Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection.
Kazer SW, Aicher TP, Muema DM, Carroll SL, Ordovas-Montanes J, Miao VN, Tu AA, Ziegler CGK, Nyquist SK, Wong EB, Ismail N, Dong M, Moodley A, Berger B, Love JC, Dong KL, Leslie A, Ndhlovu ZM, Ndung'u T, Walker BD, Shalek AK. Kazer SW, et al. Among authors: wong eb. Nat Med. 2020 Apr;26(4):511-518. doi: 10.1038/s41591-020-0799-2. Epub 2020 Mar 23. Nat Med. 2020. PMID: 32251406 Free PMC article.
Contrasting Inflammatory Signatures in Peripheral Blood and Bronchoalveolar Cells Reveal Compartment-Specific Effects of HIV Infection.
Muema DM, Mthembu M, Schiff AE, Singh U, Corleis B, Chen D, Bassett T, Rasehlo SS, Nyamande K, Khan DF, Maharaj P, Mitha M, Suleman M, Mhlane Z, Naidoo T, Ramjit D, Karim F, Kwon DS, Ndung'u T, Wong EB. Muema DM, et al. Among authors: wong eb. Front Immunol. 2020 May 19;11:864. doi: 10.3389/fimmu.2020.00864. eCollection 2020. Front Immunol. 2020. PMID: 32508817 Free PMC article.
The MAIT TCRβ chain contributes to discrimination of microbial ligand.
Narayanan GA, McLaren JE, Meermeier EW, Ladell K, Swarbrick GM, Price DA, Tran JG, Worley AH, Vogt T, Wong EB, Lewinsohn DM. Narayanan GA, et al. Among authors: wong eb. Immunol Cell Biol. 2020 Oct;98(9):770-781. doi: 10.1111/imcb.12370. Epub 2020 Jul 12. Immunol Cell Biol. 2020. PMID: 32568415 Free PMC article.
MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection.
Khuzwayo S, Mthembu M, Meermeier EW, Prakadan SM, Kazer SW, Bassett T, Nyamande K, Khan DF, Maharaj P, Mitha M, Suleman M, Mhlane Z, Ramjit D, Karim F, Shalek AK, Lewinsohn DM, Ndung'u T, Wong EB. Khuzwayo S, et al. Among authors: wong eb. Front Immunol. 2021 Apr 9;12:631410. doi: 10.3389/fimmu.2021.631410. eCollection 2021. Front Immunol. 2021. PMID: 33897687 Free PMC article.
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave.
Karim F, Gazy I, Cele S, Zungu Y, Krause R, Bernstein M, Khan K, Ganga Y, Rodel H, Mthabela N, Mazibuko M, Muema D, Ramjit D, Ndung'u T, Hanekom W, Gosnell B; COMMIT-KZN Team; Lessells RJ, Wong EB, de Oliveira T, Moosa MS, Lustig G, Leslie A, Kløverpris H, Sigal A. Karim F, et al. Among authors: wong eb. Elife. 2021 Oct 5;10:e67397. doi: 10.7554/eLife.67397. Elife. 2021. PMID: 34608862 Free PMC article.
Prevalence of Mycobacterium tuberculosis in Sputum and Reported Symptoms Among Clinic Attendees Compared With a Community Survey in Rural South Africa.
Govender I, Karat AS, Olivier S, Baisley K, Beckwith P, Dayi N, Dreyer J, Gareta D, Gunda R, Kielmann K, Koole O, Mhlongo N, Modise T, Moodley S, Mpofana X, Ndung'u T, Pillay D, Siedner MJ, Smit T, Surujdeen A, Wong EB, Grant AD. Govender I, et al. Among authors: wong eb. Clin Infect Dis. 2022 Aug 25;75(2):314-322. doi: 10.1093/cid/ciab970. Clin Infect Dis. 2022. PMID: 34864910 Free PMC article.
Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant.
Hwa SH, Snyman J, Bernstein M, Ganga Y, Cele S, Muema D, Tan CW, Khan K, Karim F, Hanekom W, Bernstein L, Kaufmann SHE, Wang LF, Ndung'u T, Sigal A; COMMIT-KZN Team. Hwa SH, et al. J Infect Dis. 2023 Jan 11;227(2):211-220. doi: 10.1093/infdis/jiac343. J Infect Dis. 2023. PMID: 35975942 Free PMC article.
91 results