Langhorne J - Search Results

1

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Among authors: langhorne j. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.

2

Malaria infection induces virus expression in human immunodeficiency virus transgenic mice by CD4 T cell-dependent immune activation.

Freitag C, Chougnet C, Schito M, Near KA, Shearer GM, Li C, Langhorne J, Sher A. Freitag C, et al. Among authors: langhorne j. J Infect Dis. 2001 Apr 15;183(8):1260-8. doi: 10.1086/319686. Epub 2001 Mar 9. J Infect Dis. 2001. PMID: 11262209

3

IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection.

Freitas do Rosário AP, Lamb T, Spence P, Stephens R, Lang A, Roers A, Muller W, O'Garra A, Langhorne J. Freitas do Rosário AP, et al. Among authors: langhorne j. J Immunol. 2012 Feb 1;188(3):1178-90. doi: 10.4049/jimmunol.1102755. Epub 2011 Dec 28. J Immunol. 2012. PMID: 22205023 Free PMC article.

4

Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner.

Brugat T, Cunningham D, Sodenkamp J, Coomes S, Wilson M, Spence PJ, Jarra W, Thompson J, Scudamore C, Langhorne J. Brugat T, et al. Among authors: langhorne j. Cell Microbiol. 2014 May;16(5):687-700. doi: 10.1111/cmi.12212. Epub 2013 Sep 30. Cell Microbiol. 2014. PMID: 24003897 Free PMC article.

5

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells.

Coomes SM, Pelly VS, Kannan Y, Okoye IS, Czieso S, Entwistle LJ, Perez-Lloret J, Nikolov N, Potocnik AJ, Biró J, Langhorne J, Wilson MS. Coomes SM, et al. Among authors: langhorne j. PLoS Pathog. 2015 Jul 6;11(7):e1004994. doi: 10.1371/journal.ppat.1004994. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26147567 Free PMC article.

6

Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria.

Capuccini B, Lin J, Talavera-López C, Khan SM, Sodenkamp J, Spaccapelo R, Langhorne J. Capuccini B, et al. Among authors: langhorne j. Sci Rep. 2016 Dec 19;6:39258. doi: 10.1038/srep39258. Sci Rep. 2016. PMID: 27991544 Free PMC article.

7

Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria.

Lin JW, Sodenkamp J, Cunningham D, Deroost K, Tshitenge TC, McLaughlin S, Lamb TJ, Spencer-Dene B, Hosking C, Ramesar J, Janse CJ, Graham C, O'Garra A, Langhorne J. Lin JW, et al. Among authors: langhorne j. Sci Rep. 2017 Feb 3;7:41722. doi: 10.1038/srep41722. Sci Rep. 2017. PMID: 28155887 Free PMC article.

8

ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model.

Cunningham DA, Lin JW, Brugat T, Jarra W, Tumwine I, Kushinga G, Ramesar J, Franke-Fayard B, Langhorne J. Cunningham DA, et al. Among authors: langhorne j. Malar J. 2017 May 3;16(1):185. doi: 10.1186/s12936-017-1834-8. Malar J. 2017. PMID: 28468674 Free PMC article.

9

T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection.

Moreira-Teixeira L, Redford PS, Stavropoulos E, Ghilardi N, Maynard CL, Weaver CT, Freitas do Rosário AP, Wu X, Langhorne J, O'Garra A. Moreira-Teixeira L, et al. Among authors: langhorne j. J Immunol. 2017 Jul 15;199(2):613-623. doi: 10.4049/jimmunol.1601340. Epub 2017 Jun 5. J Immunol. 2017. PMID: 28584007 Free PMC article.

10

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4⁺ T cells.

Gabryšová L, Alvarez-Martinez M, Luisier R, Cox LS, Sodenkamp J, Hosking C, Pérez-Mazliah D, Whicher C, Kannan Y, Potempa K, Wu X, Bhaw L, Wende H, Sieweke MH, Elgar G, Wilson M, Briscoe J, Metzis V, Langhorne J, Luscombe NM, O'Garra A. Gabryšová L, et al. Among authors: langhorne j. Nat Immunol. 2018 May;19(5):497-507. doi: 10.1038/s41590-018-0083-5. Epub 2018 Apr 16. Nat Immunol. 2018. PMID: 29662170 Free PMC article.

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