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Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium.
Brandt R, Sell T, Lüthen M, Uhlitz F, Klinger B, Riemer P, Giesecke-Thiel C, Schulze S, El-Shimy IA, Kunkel D, Fauler B, Mielke T, Mages N, Herrmann BG, Sers C, Blüthgen N, Morkel M. Brandt R, et al. Among authors: klinger b. Nat Commun. 2019 Jul 2;10(1):2919. doi: 10.1038/s41467-019-10954-y. Nat Commun. 2019. PMID: 31266962 Free PMC article.
Discovering causal signaling pathways through gene-expression patterns.
Parikh JR, Klinger B, Xia Y, Marto JA, Blüthgen N. Parikh JR, et al. Among authors: klinger b. Nucleic Acids Res. 2010 Jul;38(Web Server issue):W109-17. doi: 10.1093/nar/gkq424. Epub 2010 May 21. Nucleic Acids Res. 2010. PMID: 20494976 Free PMC article.
Multilevel regulation of HIF-1 signaling by TTP.
Fähling M, Persson AB, Klinger B, Benko E, Steege A, Kasim M, Patzak A, Persson PB, Wolf G, Blüthgen N, Mrowka R. Fähling M, et al. Among authors: klinger b. Mol Biol Cell. 2012 Oct;23(20):4129-41. doi: 10.1091/mbc.E11-11-0949. Epub 2012 Aug 23. Mol Biol Cell. 2012. PMID: 22918951 Free PMC article.
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.
Rohwer N, Bindel F, Grimm C, Lin SJ, Wappler J, Klinger B, Blüthgen N, Du Bois I, Schmeck B, Lehrach H, de Graauw M, Goncalves E, Saez-Rodriguez J, Tan P, Grabsch HI, Prigione A, Kempa S, Cramer T. Rohwer N, et al. Among authors: klinger b. Oncotarget. 2016 Feb 9;7(6):6693-710. doi: 10.18632/oncotarget.6793. Oncotarget. 2016. PMID: 26760764 Free PMC article.
An immediate-late gene expression module decodes ERK signal duration.
Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, Klinger B, Blüthgen N. Uhlitz F, et al. Among authors: klinger b. Mol Syst Biol. 2017 May 3;13(5):928. doi: 10.15252/msb.20177554. Mol Syst Biol. 2017. PMID: 28468958 Free PMC article.
100 results