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Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment.
Smith N, Rodero MP, Bekaddour N, Bondet V, Ruiz-Blanco YB, Harms M, Mayer B, Bader-Meunier B, Quartier P, Bodemer C, Baudouin V, Dieudonné Y, Kirchhoff F, Sanchez Garcia E, Charbit B, Leboulanger N, Jahrsdörfer B, Richard Y, Korganow AS, Münch J, Nisole S, Duffy D, Herbeuval JP. Smith N, et al. Among authors: jahrsdorfer b. Sci Adv. 2019 Jul 10;5(7):eaav9019. doi: 10.1126/sciadv.aav9019. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31309143 Free PMC article.
Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants.
Groß R, Zanoni M, Seidel A, Conzelmann C, Gilg A, Krnavek D, Erdemci-Evin S, Mayer B, Hoffmann M, Pöhlmann S, Liu W, Hahn BH, Beil A, Kroschel J, Jahrsdörfer B, Schrezenmeier H, Kirchhoff F, Münch J, Müller JA. Groß R, et al. Among authors: jahrsdorfer b. EBioMedicine. 2022 Jan;75:103761. doi: 10.1016/j.ebiom.2021.103761. Epub 2021 Dec 17. EBioMedicine. 2022. PMID: 34929493 Free PMC article. Clinical Trial.
SARS-CoV-2 vaccination of convalescents boosts neutralization capacity against Omicron subvariants BA.1, BA.2 and BA.5 and can be predicted by anti-S antibody concentrations in serological assays.
Seidel A, Hoffmann S, Jahrsdörfer B, Körper S, Ludwig C, Vieweg C, Albers D, von Maltitz P, Müller R, Lotfi R, Wuchter P, Klüter H, Kirchhoff F, Schmidt M, Münch J, Schrezenmeier H. Seidel A, et al. Among authors: jahrsdorfer b. Front Immunol. 2023 Apr 25;14:1170759. doi: 10.3389/fimmu.2023.1170759. eCollection 2023. Front Immunol. 2023. PMID: 37180152 Free PMC article.
CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B.
Hagn M, Ebel V, Sontheimer K, Schwesinger E, Lunov O, Beyer T, Fabricius D, Barth TF, Viardot A, Stilgenbauer S, Hepp J, Scharffetter-Kochanek K, Simmet T, Jahrsdörfer B. Hagn M, et al. Among authors: jahrsdorfer b. Eur J Immunol. 2010 Jul;40(7):2060-9. doi: 10.1002/eji.200940113. Eur J Immunol. 2010. PMID: 20394077 Free article.
Interleukin 21-induced granzyme B-expressing B cells infiltrate tumors and regulate T cells.
Lindner S, Dahlke K, Sontheimer K, Hagn M, Kaltenmeier C, Barth TF, Beyer T, Reister F, Fabricius D, Lotfi R, Lunov O, Nienhaus GU, Simmet T, Kreienberg R, Möller P, Schrezenmeier H, Jahrsdörfer B. Lindner S, et al. Among authors: jahrsdorfer b. Cancer Res. 2013 Apr 15;73(8):2468-79. doi: 10.1158/0008-5472.CAN-12-3450. Epub 2013 Feb 5. Cancer Res. 2013. PMID: 23384943
CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients.
Kaltenmeier C, Gawanbacht A, Beyer T, Lindner S, Trzaska T, van der Merwe JA, Härter G, Grüner B, Fabricius D, Lotfi R, Schwarz K, Schütz C, Hönig M, Schulz A, Kern P, Bommer M, Schrezenmeier H, Kirchhoff F, Jahrsdörfer B. Kaltenmeier C, et al. Among authors: jahrsdorfer b. J Immunol. 2015 Apr 15;194(8):3768-77. doi: 10.4049/jimmunol.1402568. Epub 2015 Mar 16. J Immunol. 2015. PMID: 25780036
An enzyme-based immunodetection assay to quantify SARS-CoV-2 infection.
Conzelmann C, Gilg A, Groß R, Schütz D, Preising N, Ständker L, Jahrsdörfer B, Schrezenmeier H, Sparrer KMJ, Stamminger T, Stenger S, Münch J, Müller JA. Conzelmann C, et al. Among authors: jahrsdorfer b. Antiviral Res. 2020 Sep;181:104882. doi: 10.1016/j.antiviral.2020.104882. Epub 2020 Jul 29. Antiviral Res. 2020. PMID: 32738255 Free PMC article.
High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection.
Jacobsen EM, Fabricius D, Class M, Topfstedt F, Lorenzetti R, Janowska I, Schmidt F, Staniek J, Zernickel M, Stamminger T, Dietz AN, Zellmer A, Hecht M, Rauch P, Blum C, Ludwig C, Jahrsdörfer B, Schrezenmeier H, Heeg M, Mayer B, Seidel A, Groß R, Münch J, Kirchhoff F, Bode SFN, Strauss G, Renk H, Elling R, Stich M, Voll RE, Tönshof B, Franz AR, Henneke P, Debatin KM, Rizzi M, Janda A. Jacobsen EM, et al. Among authors: jahrsdorfer b. Nat Commun. 2022 Nov 28;13(1):7315. doi: 10.1038/s41467-022-35055-1. Nat Commun. 2022. PMID: 36437276 Free PMC article.
70 results