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The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability.
Gandhi DM, Rosas R Jr, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C. Gandhi DM, et al. Among authors: weiler h. Bioorg Med Chem. 2019 Sep 1;27(17):3788-3796. doi: 10.1016/j.bmc.2019.06.043. Epub 2019 Jun 29. Bioorg Med Chem. 2019. PMID: 31320211 Free PMC article.
Bleeding diathesis in mice lacking JAK2 in platelets.
Eaton N, Subramaniam S, Schulte ML, Drew C, Jakab D, Haberichter SL, Weiler H, Falet H. Eaton N, et al. Among authors: weiler h. Blood Adv. 2021 Aug 10;5(15):2969-2981. doi: 10.1182/bloodadvances.2020003032. Blood Adv. 2021. PMID: 34342643 Free PMC article.
Role of thrombomodulin expression on hematopoietic stem cells.
Basu S, Liang HPH, Hernandez I, Zogg M, Fields B, May J, Ogoti Y, Wyseure T, Mosnier LO, Burns RT, Carlson K, Weiler H. Basu S, et al. Among authors: weiler h. J Thromb Haemost. 2020 Jan;18(1):123-135. doi: 10.1111/jth.14663. Epub 2019 Nov 6. J Thromb Haemost. 2020. PMID: 31628891 Free PMC article.
407 results