Brems H - Search Results

1

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.

Boretto M, Maenhoudt N, Luo X, Hennes A, Boeckx B, Bui B, Heremans R, Perneel L, Kobayashi H, Van Zundert I, Brems H, Cox B, Ferrante M, Uji-I H, Koh KP, D'Hooghe T, Vanhie A, Vergote I, Meuleman C, Tomassetti C, Lambrechts D, Vriens J, Timmerman D, Vankelecom H. Boretto M, et al. Among authors: brems h. Nat Cell Biol. 2019 Aug;21(8):1041-1051. doi: 10.1038/s41556-019-0360-z. Epub 2019 Aug 1. Nat Cell Biol. 2019. PMID: 31371824

2

Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis.

Magallón-Lorenz M, Terribas E, Ortega-Bertran S, Creus-Bachiller E, Fernández M, Requena G, Rosas I, Mazuelas H, Uriarte-Arrazola I, Negro A, Lausová T, Castellanos E, Blanco I, DeVries G, Kawashima H, Legius E, Brems H, Mautner V, Kluwe L, Ratner N, Wallace M, Fernández-Rodriguez J, Lázaro C, Fletcher JA, Reuss D, Carrió M, Gel B, Serra E. Magallón-Lorenz M, et al. Among authors: brems h. iScience. 2023 Jan 31;26(2):106096. doi: 10.1016/j.isci.2023.106096. eCollection 2023 Feb 17. iScience. 2023. PMID: 36818284 Free PMC article.

3

Preimplantation genetic diagnosis using fluorescent in situ hybridization for cancer predisposition syndromes caused by microdeletions.

Vanneste E, Melotte C, Debrock S, D'Hooghe T, Brems H, Fryns JP, Legius E, Vermeesch JR. Vanneste E, et al. Among authors: brems h. Hum Reprod. 2009 Jun;24(6):1522-8. doi: 10.1093/humrep/dep034. Epub 2009 Mar 10. Hum Reprod. 2009. PMID: 19278970

4

Analysis of 108 patients with endometrial carcinoma using the PROMISE classification and additional genetic analyses for MMR-D.

Timmerman S, Van Rompuy AS, Van Gorp T, Vanden Bempt I, Brems H, Van Nieuwenhuysen E, Han SN, Neven P, Victoor J, Laenen A, Vergote I. Timmerman S, et al. Among authors: brems h. Gynecol Oncol. 2020 Apr;157(1):245-251. doi: 10.1016/j.ygyno.2020.01.019. Epub 2020 Jan 21. Gynecol Oncol. 2020. PMID: 31980219

5

Comprehensive immunomolecular profiling of endometrial carcinoma: A tertiary retrospective study.

Victoor J, Borght SV, Spans L, Lehnert S, Brems H, Laenen A, Vergote I, Van Gorp T, Van Nieuwenhuysen E, Han S, Timmerman S, Van Rompuy AS, Vanden Bempt I. Victoor J, et al. Among authors: brems h. Gynecol Oncol. 2021 Sep;162(3):694-701. doi: 10.1016/j.ygyno.2021.06.030. Epub 2021 Jul 10. Gynecol Oncol. 2021. PMID: 34253388

6

Preclinical workup using long-read amplicon sequencing provides families with de novo pathogenic variants access to universal preimplantation genetic testing.

Tsuiko O, El Ayeb Y, Jatsenko T, Allemeersch J, Melotte C, Ding J, Debrock S, Peeraer K, Vanhie A, De Leener A, Pirard C, Kluyskens C, Denayer E, Legius E, Vermeesch JR, Brems H, Dimitriadou E. Tsuiko O, et al. Among authors: brems h. Hum Reprod. 2023 Mar 1;38(3):511-519. doi: 10.1093/humrep/deac273. Hum Reprod. 2023. PMID: 36625546

7

Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.

Brems H, Chmara M, Sahbatou M, Denayer E, Taniguchi K, Kato R, Somers R, Messiaen L, De Schepper S, Fryns JP, Cools J, Marynen P, Thomas G, Yoshimura A, Legius E. Brems H, et al. Nat Genet. 2007 Sep;39(9):1120-6. doi: 10.1038/ng2113. Epub 2007 Aug 19. Nat Genet. 2007. PMID: 17704776

8

PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.

De Raedt T, Beert E, Pasmant E, Luscan A, Brems H, Ortonne N, Helin K, Hornick JL, Mautner V, Kehrer-Sawatzki H, Clapp W, Bradner J, Vidaud M, Upadhyaya M, Legius E, Cichowski K. De Raedt T, et al. Among authors: brems h. Nature. 2014 Oct 9;514(7521):247-51. doi: 10.1038/nature13561. Epub 2014 Aug 13. Nature. 2014. PMID: 25119042

9

Conservation of hotspots for recombination in low-copy repeats associated with the NF1 microdeletion.

Raedt TD, Stephens M, Heyns I, Brems H, Thijs D, Messiaen L, Stephens K, Lazaro C, Wimmer K, Kehrer-Sawatzki H, Vidaud D, Kluwe L, Marynen P, Legius E. Raedt TD, et al. Among authors: brems h. Nat Genet. 2006 Dec;38(12):1419-23. doi: 10.1038/ng1920. Epub 2006 Nov 19. Nat Genet. 2006. PMID: 17115058

10

Multiple pilomatricomas with somatic CTNNB1 mutations in children with constitutive mismatch repair deficiency.

Chmara M, Wernstedt A, Wasag B, Peeters H, Renard M, Beert E, Brems H, Giner T, Bieber I, Hamm H, Sciot R, Wimmer K, Legius E. Chmara M, et al. Among authors: brems h. Genes Chromosomes Cancer. 2013 Jul;52(7):656-64. doi: 10.1002/gcc.22061. Epub 2013 Apr 30. Genes Chromosomes Cancer. 2013. PMID: 23629955

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