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mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding.
Delarue M, Brittingham GP, Pfeffer S, Surovtsev IV, Pinglay S, Kennedy KJ, Schaffer M, Gutierrez JI, Sang D, Poterewicz G, Chung JK, Plitzko JM, Groves JT, Jacobs-Wagner C, Engel BD, Holt LJ. Delarue M, et al. Among authors: pinglay s. Cell. 2018 Jul 12;174(2):338-349.e20. doi: 10.1016/j.cell.2018.05.042. Epub 2018 Jun 21. Cell. 2018. PMID: 29937223 Free PMC article.
Resurrecting essential amino acid biosynthesis in mammalian cells.
Trolle J, McBee RM, Kaufman A, Pinglay S, Berger H, German S, Liu L, Shen MJ, Guo X, Martin JA, Pacold ME, Jones DR, Boeke JD, Wang HH. Trolle J, et al. Among authors: pinglay s. Elife. 2022 Sep 27;11:e72847. doi: 10.7554/eLife.72847. Elife. 2022. PMID: 36165439 Free PMC article.
A versatile platform for locus-scale genome rewriting and verification.
Brosh R, Laurent JM, Ordoñez R, Huang E, Hogan MS, Hitchcock AM, Mitchell LA, Pinglay S, Cadley JA, Luther RD, Truong DM, Boeke JD, Maurano MT. Brosh R, et al. Among authors: pinglay s. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2023952118. doi: 10.1073/pnas.2023952118. Proc Natl Acad Sci U S A. 2021. PMID: 33649239 Free PMC article.
De novo assembly and delivery to mouse cells of a 101 kb functional human gene.
Mitchell LA, McCulloch LH, Pinglay S, Berger H, Bosco N, Brosh R, Bulajić M, Huang E, Hogan MS, Martin JA, Mazzoni EO, Davoli T, Maurano MT, Boeke JD. Mitchell LA, et al. Among authors: pinglay s. Genetics. 2021 May 17;218(1):iyab038. doi: 10.1093/genetics/iyab038. Genetics. 2021. PMID: 33742653 Free PMC article.
Context-dependent neocentromere activity in synthetic yeast chromosome VIII.
Lauer S, Luo J, Lazar-Stefanita L, Zhang W, McCulloch LH, Fanfani V, Lobzaev E, Haase MAB, Easo N, Zhao Y, Yu F, Cai J; Build-A-Genome Class; Bader JS, Stracquadanio G, Boeke JD. Lauer S, et al. Cell Genom. 2023 Nov 9;3(11):100437. doi: 10.1016/j.xgen.2023.100437. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020969 Free PMC article.