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Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.
Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH. Kim IS, et al. Among authors: sreekumar a. Nat Cell Biol. 2019 Sep;21(9):1113-1126. doi: 10.1038/s41556-019-0373-7. Epub 2019 Aug 26. Nat Cell Biol. 2019. PMID: 31451770 Free PMC article.
CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC.
Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. Kang YK, et al. Among authors: sreekumar a. PLoS Genet. 2015 Apr 1;11(4):e1005116. doi: 10.1371/journal.pgen.1005116. eCollection 2015 Apr. PLoS Genet. 2015. PMID: 25830341 Free PMC article.
Analytical strategies for studying stem cell metabolism.
Arnold JM, Choi WT, Sreekumar A, Maletić-Savatić M. Arnold JM, et al. Among authors: sreekumar a. Front Biol (Beijing). 2015 Apr;10(2):141-153. doi: 10.1007/s11515-015-1357-z. Front Biol (Beijing). 2015. PMID: 26213533 Free PMC article.
Metabolomic profiling of hormone-dependent cancers: a bird's eye view.
Lloyd SM, Arnold J, Sreekumar A. Lloyd SM, et al. Among authors: sreekumar a. Trends Endocrinol Metab. 2015 Sep;26(9):477-85. doi: 10.1016/j.tem.2015.07.001. Epub 2015 Aug 1. Trends Endocrinol Metab. 2015. PMID: 26242817 Free PMC article. Review.
EMT-induced metabolite signature identifies poor clinical outcome.
Bhowmik SK, Ramirez-Peña E, Arnold JM, Putluri V, Sphyris N, Michailidis G, Putluri N, Ambs S, Sreekumar A, Mani SA. Bhowmik SK, et al. Among authors: sreekumar a. Oncotarget. 2015 Dec 15;6(40):42651-60. doi: 10.18632/oncotarget.4765. Oncotarget. 2015. PMID: 26315396 Free PMC article.
Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.
Park JH, Vithayathil S, Kumar S, Sung PL, Dobrolecki LE, Putluri V, Bhat VB, Bhowmik SK, Gupta V, Arora K, Wu D, Tsouko E, Zhang Y, Maity S, Donti TR, Graham BH, Frigo DE, Coarfa C, Yotnda P, Putluri N, Sreekumar A, Lewis MT, Creighton CJ, Wong LC, Kaipparettu BA. Park JH, et al. Among authors: sreekumar a. Cell Rep. 2016 Mar 8;14(9):2154-2165. doi: 10.1016/j.celrep.2016.02.004. Epub 2016 Feb 25. Cell Rep. 2016. PMID: 26923594 Free PMC article.
Promoter Methylation Modulates Indoleamine 2,3-Dioxygenase 1 Induction by Activated T Cells in Human Breast Cancers.
Noonepalle SK, Gu F, Lee EJ, Choi JH, Han Q, Kim J, Ouzounova M, Shull AY, Pei L, Hsu PY, Kolhe R, Shi F, Choi J, Chiou K, Huang TH, Korkaya H, Deng L, Xin HB, Huang S, Thangaraju M, Sreekumar A, Ambs S, Tang SC, Munn DH, Shi H. Noonepalle SK, et al. Among authors: sreekumar a. Cancer Immunol Res. 2017 Apr;5(4):330-344. doi: 10.1158/2326-6066.CIR-16-0182. Epub 2017 Mar 6. Cancer Immunol Res. 2017. PMID: 28264810 Free PMC article.
Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming.
Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, Sheng K, Dobrolecki LE, Zhang X, Putluri N, Phung TL, Mani SA, Stossi F, Sreekumar A, Mancini MA, Decker WK, Zong C, Lewis MT, Zhang XH. Tian L, et al. Among authors: sreekumar a. Nature. 2017 Apr 13;544(7649):250-254. doi: 10.1038/nature21724. Epub 2017 Apr 3. Nature. 2017. PMID: 28371798 Free PMC article.
154 results