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A Genotype-Guided Strategy for Oral P2Y12 Inhibitors in Primary PCI.
Claassens DMF, Vos GJA, Bergmeijer TO, Hermanides RS, van 't Hof AWJ, van der Harst P, Barbato E, Morisco C, Tjon Joe Gin RM, Asselbergs FW, Mosterd A, Herrman JR, Dewilde WJM, Janssen PWA, Kelder JC, Postma MJ, de Boer A, Boersma C, Deneer VHM, Ten Berg JM. Claassens DMF, et al. Among authors: de boer a. N Engl J Med. 2019 Oct 24;381(17):1621-1631. doi: 10.1056/NEJMoa1907096. Epub 2019 Sep 3. N Engl J Med. 2019. PMID: 31479209 Clinical Trial.
Besides CYP2C19*2, the variant allele CYP2C9*3 is associated with higher on-clopidogrel platelet reactivity in patients on dual antiplatelet therapy undergoing elective coronary stent implantation.
Harmsze A, van Werkum JW, Bouman HJ, Ruven HJ, Breet NJ, Ten Berg JM, Hackeng CM, Tjoeng MM, Klungel OH, de Boer A, Deneer VH. Harmsze A, et al. Among authors: de boer a. Pharmacogenet Genomics. 2010 Jan;20(1):18-25. doi: 10.1097/FPC.0b013e328333dafe. Pharmacogenet Genomics. 2010. PMID: 19934793
[Genetic variations affect drug safety and efficacy].
Harmsze AM, Deneer VH, Maitland-van der Zee AH, de Boer A, Klungel OH. Harmsze AM, et al. Among authors: de boer a. Ned Tijdschr Geneeskd. 2010;154:A1503. Ned Tijdschr Geneeskd. 2010. PMID: 20699026 Review. Dutch.
CYP2C19 and ABCB1 genes and individualized treatment with clopidogrel.
Peters BJ, Harmsze AM, ten Berg JM, Maitland-van der Zee AH, Tjoeng MM, de Boer A, Deneer VH. Peters BJ, et al. Among authors: de boer a. Pharmacogenomics. 2011 Feb;12(2):141-4. doi: 10.2217/pgs.10.211. Pharmacogenomics. 2011. PMID: 21332306 No abstract available.
[Interaction between clopidogrel and proton pump inhibitors].
Harmsze AM, de Boer A, Boot H, Deneer VH, Heringa M, Mol PG, Schalekamp T, Verduijn MM, Verheugt FW, le Comte M. Harmsze AM, et al. Among authors: de boer a. Ned Tijdschr Geneeskd. 2011;155(28):A2442. Ned Tijdschr Geneeskd. 2011. PMID: 21771377 Review. Dutch.
1,377 results