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Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C Jr. Dias Viegas FP, et al. Among authors: machado rp. Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29421570
A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells.
Oliveira MS, Barbosa MIF, de Souza TB, Moreira DRM, Martins FT, Villarreal W, Machado RP, Doriguetto AC, Soares MBP, Bezerra DP. Oliveira MS, et al. Among authors: machado rp. Redox Biol. 2019 Jan;20:182-194. doi: 10.1016/j.redox.2018.10.006. Epub 2018 Oct 12. Redox Biol. 2019. PMID: 30359932 Free PMC article.
Screening for coronavirus disease 2019 in pregnant women admitted for delivery: an observational study.
Cavalcante ANM, Almeida RLF, Oliveira DN, Lima DM, Cavalcante CTMB, Tavares LVS, Almeida RP, Machado RPG, Araujo Júnior E, Cavalcante MB. Cavalcante ANM, et al. Among authors: machado rpg. Rev Assoc Med Bras (1992). 2023 Jul 17;69(7):e20230084. doi: 10.1590/1806-9282.20230084. eCollection 2023. Rev Assoc Med Bras (1992). 2023. PMID: 37466595 Free PMC article.
Follow-up of participants with subjective cognitive decline from Tremembé epidemiologic study, Brazil.
César-Freitas KG, Berardis ACP, Pretto TVM, Viagi AM, Lourençon V, Zanini LYK, Barbosa ICC, Machado RP, Cunha NGM, Watanabe MJL, Cecchini MA, Brucki SMD, Nitrini R. César-Freitas KG, et al. Among authors: machado rp. Dement Neuropsychol. 2023 May 29;17:e20220064. doi: 10.1590/1980-5764-DN-2022-0064. eCollection 2023. Dement Neuropsychol. 2023. PMID: 37261255 Free PMC article.
Hemostasis profile in COVID-19 infection.
Duarte FB, Machado RPG, Lemes RPG, Duarte IA, Duarte BA, Machado CMG, Duarte JVA, Rocha SGMD, Moura ATG, Holanda RARR. Duarte FB, et al. Among authors: machado rpg. Rev Assoc Med Bras (1992). 2020 May;66(5):571-572. doi: 10.1590/1806-9282.66.5.571. Epub 2020 Jul 3. Rev Assoc Med Bras (1992). 2020. PMID: 32638971 Free article. No abstract available.
26 results