Ploeg EM - Search Results

1

Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC.

Essers PBM, van der Heijden M, Verhagen CVM, Ploeg EM, de Roest RH, Leemans CR, Brakenhoff RH, van den Brekel MWM, Bartelink H, Verheij M, Vens C. Essers PBM, et al. Among authors: ploeg em. Cancer Res. 2019 Nov 1;79(21):5597-5611. doi: 10.1158/0008-5472.CAN-18-3388. Epub 2019 Sep 12. Cancer Res. 2019. PMID: 31515237

2

Bispecific antibody CD73xEpCAM selectively inhibits the adenosine-mediated immunosuppressive activity of carcinoma-derived extracellular vesicles.

Ploeg EM, Ke X, Britsch I, Hendriks MAJM, Van der Zant FA, Kruijff S, Samplonius DF, Zhang H, Helfrich W. Ploeg EM, et al. Cancer Lett. 2021 Aug 28;521:109-118. doi: 10.1016/j.canlet.2021.08.037. Online ahead of print. Cancer Lett. 2021. PMID: 34464670 Free article.

3

Cationic amphiphilic drugs as potential anticancer therapy for bladder cancer.

van der Horst G, van de Merbel AF, Ruigrok E, van der Mark MH, Ploeg E, Appelman L, Tvingsholm S, Jäätelä M, van Uhm J, Kruithof-de Julio M, Thalmann GN, Pelger RCM, Bangma CH, Boormans JL, van der Pluijm G, Zwarthoff EC. van der Horst G, et al. Mol Oncol. 2020 Dec;14(12):3121-3134. doi: 10.1002/1878-0261.12793. Epub 2020 Oct 16. Mol Oncol. 2020. PMID: 32896947 Free PMC article.

4

The In Vitro Response of Tissue Stem Cells to Irradiation With Different Linear Energy Transfers.

Nagle PW, Hosper NA, Ploeg EM, van Goethem MJ, Brandenburg S, Langendijk JA, Chiu RK, Coppes RP. Nagle PW, et al. Among authors: ploeg em. Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):103-111. doi: 10.1016/j.ijrobp.2016.02.020. Epub 2016 Feb 12. Int J Radiat Oncol Biol Phys. 2016. PMID: 27084633 Free article.

5

Bispecific antibody approach for EGFR-directed blockade of the CD47-SIRPα "don't eat me" immune checkpoint promotes neutrophil-mediated trogoptosis and enhances antigen cross-presentation.

Hendriks MAJM, Ploeg EM, Koopmans I, Britsch I, Ke X, Samplonius DF, Helfrich W. Hendriks MAJM, et al. Among authors: ploeg em. Oncoimmunology. 2020 Sep 29;9(1):1824323. doi: 10.1080/2162402X.2020.1824323. Oncoimmunology. 2020. PMID: 33299654 Free PMC article.

6

Cancer cells under immune attack acquire CD47-mediated adaptive immune resistance independent of the myeloid CD47-SIRPα axis.

Hendriks MAJM, Britsch I, Ke X, van Wijngarden AP, Samplonius DF, Ploeg EM, Helfrich W. Hendriks MAJM, et al. Among authors: ploeg em. Oncoimmunology. 2021 Nov 20;10(1):2005344. doi: 10.1080/2162402X.2021.2005344. eCollection 2021. Oncoimmunology. 2021. PMID: 34858730 Free PMC article.

7

A proof-of-concept study on the use of a fluorescein-based ¹⁸F-tracer for pretargeted PET.

Helbert H, Ploeg EM, Samplonius DF, Blok SN, Antunes IF, Böhmer VI, Luurtsema G, Dierckx RAJO, Feringa BL, Elsinga PH, Szymanski W, Helfrich W. Helbert H, et al. Among authors: ploeg em. EJNMMI Radiopharm Chem. 2022 Mar 3;7(1):3. doi: 10.1186/s41181-022-00155-2. EJNMMI Radiopharm Chem. 2022. PMID: 35239034 Free PMC article.

8

Impact of cumulative complications on 1-year treatment-related healthcare costs in patients with colorectal peritoneal metastases undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.

van der Zant FA, Kooijman BJL, Hentzen JEKR, Helfrich W, Ploeg EM, van Ginkel RJ, van Leeuwen BL, Been LB, Klaase JM, Hemmer PHJ, van der Hilst CS, Kruijff S. van der Zant FA, et al. Among authors: ploeg em. BJS Open. 2022 Sep 2;6(5):zrac109. doi: 10.1093/bjsopen/zrac109. BJS Open. 2022. PMID: 36218348 Free PMC article.

9

Bispecific antibody CD73xEGFR more selectively inhibits the CD73/adenosine immune checkpoint on cancer cells and concurrently counteracts pro-oncogenic activities of CD73 and EGFR.

Ploeg EM, Samplonius DF, Xiong X, Ke X, Hendriks MAJM, Britsch I, van Wijngaarden AP, Zhang H, Helfrich W. Ploeg EM, et al. J Immunother Cancer. 2023 Sep;11(9):e006837. doi: 10.1136/jitc-2023-006837. J Immunother Cancer. 2023. PMID: 37734877 Free PMC article.

10

A Novel Bispecific Antibody for EpCAM-Directed Inhibition of the CD73/Adenosine Immune Checkpoint in Ovarian Cancer.

Ploeg EM, Britsch I, van Wijngaarden AP, Ke X, Hendriks MAJM, Samplonius DF, Helfrich W. Ploeg EM, et al. Cancers (Basel). 2023 Jul 17;15(14):3651. doi: 10.3390/cancers15143651. Cancers (Basel). 2023. PMID: 37509310 Free PMC article.

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