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Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology.
Nat Commun. 2019 Sep 25;10(1):4364. doi: 10.1038/s41467-019-12311-5.
Nat Commun. 2019.
PMID: 31554793
Free PMC article.
Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans.
Takeda AJ, Zhang Y, Dornan GL, Siempelkamp BD, Jenkins ML, Matthews HF, McElwee JJ, Bi W, Seeborg FO, Su HC, Burke JE, Lucas CL.
Takeda AJ, et al.
J Allergy Clin Immunol. 2017 Oct;140(4):1152-1156.e10. doi: 10.1016/j.jaci.2017.03.026. Epub 2017 Apr 13.
J Allergy Clin Immunol. 2017.
PMID: 28414062
Free PMC article.
No abstract available.
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