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Open Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences.
Lippert J, Burghaus R, Edginton A, Frechen S, Karlsson M, Kovar A, Lehr T, Milligan P, Nock V, Ramusovic S, Riggs M, Schaller S, Schlender J, Schmidt S, Sevestre M, Sjögren E, Solodenko J, Staab A, Teutonico D. Lippert J, et al. CPT Pharmacometrics Syst Pharmacol. 2019 Dec;8(12):878-882. doi: 10.1002/psp4.12473. Epub 2019 Nov 12. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31671256 Free PMC article. Review. No abstract available.
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
Frechen S, Solodenko J, Wendl T, Dallmann A, Ince I, Lehr T, Lippert J, Burghaus R. Frechen S, et al. Among authors: lippert j. CPT Pharmacometrics Syst Pharmacol. 2021 Jun;10(6):633-644. doi: 10.1002/psp4.12636. Epub 2021 May 24. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33946131 Free PMC article.
Modeling and Simulation of In Vivo Drug Effects.
Lippert J, Burghaus R, Kuepfer L, Ploeger B, Schaller S, Schmitt W, Willmann S. Lippert J, et al. Handb Exp Pharmacol. 2016;232:313-29. doi: 10.1007/164_2015_21. Handb Exp Pharmacol. 2016. PMID: 26578524 Review.
Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
Ince I, Solodenko J, Frechen S, Dallmann A, Niederalt C, Schlender J, Burghaus R, Lippert J, Willmann S. Ince I, et al. Among authors: lippert j. J Clin Pharmacol. 2019 Sep;59 Suppl 1:S95-S103. doi: 10.1002/jcph.1497. J Clin Pharmacol. 2019. PMID: 31502689 Review.
Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation.
EFPIA MID3 Workgroup; Marshall SF, Burghaus R, Cosson V, Cheung SY, Chenel M, DellaPasqua O, Frey N, Hamrén B, Harnisch L, Ivanow F, Kerbusch T, Lippert J, Milligan PA, Rohou S, Staab A, Steimer JL, Tornøe C, Visser SA. EFPIA MID3 Workgroup, et al. Among authors: lippert j. CPT Pharmacometrics Syst Pharmacol. 2016 Mar;5(3):93-122. doi: 10.1002/psp4.12049. Epub 2016 Mar 14. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27069774 Free PMC article.
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
Ince I, Dallmann A, Frechen S, Coboeken K, Niederalt C, Wendl T, Block M, Meyer M, Eissing T, Burghaus R, Lippert J, Willmann S, Schlender JF. Ince I, et al. Among authors: lippert j. J Clin Pharmacol. 2021 Jun;61 Suppl 1(Suppl 1):S70-S82. doi: 10.1002/jcph.1869. J Clin Pharmacol. 2021. PMID: 34185905 Free PMC article.
Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.
Fendt R, Hofmann U, Schneider ARP, Schaeffeler E, Burghaus R, Yilmaz A, Blank LM, Kerb R, Lippert J, Schlender JF, Schwab M, Kuepfer L. Fendt R, et al. Among authors: lippert j. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):782-793. doi: 10.1002/psp4.12646. Epub 2021 Jun 26. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34053199 Free PMC article. Clinical Trial.
Establishing a Multidisciplinary Framework to Study Drug-Drug Interactions of Hormonal Contraceptives: An Invitation to Collaborate.
Lesko LJ, Vozmediano V, Brown JD, Winterstein A, Zhao P, Lippert J, Höchel J, Chaturvedula A, White A, Schmidt S. Lesko LJ, et al. Among authors: lippert j. CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):706-708. doi: 10.1002/psp4.12357. Epub 2018 Oct 23. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30260082 Free PMC article.
195 results