Gasparini L - Search Results

1

N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain.

Schlegel K, Awwad K, Heym RG, Holzinger D, Doell A, Barghorn S, Jahn TR, Klein C, Mordashova Y, Schulz M, Gasparini L. Schlegel K, et al. Among authors: gasparini l. Acta Neuropathol Commun. 2019 Nov 13;7(1):177. doi: 10.1186/s40478-019-0831-2. Acta Neuropathol Commun. 2019. PMID: 31722749 Free PMC article.

2

Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy.

Barini E, Antico O, Zhao Y, Asta F, Tucci V, Catelani T, Marotta R, Xu H, Gasparini L. Barini E, et al. Among authors: gasparini l. Mol Neurodegener. 2016 Feb 9;11:16. doi: 10.1186/s13024-016-0082-7. Mol Neurodegener. 2016. PMID: 26858121 Free PMC article.

3

SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer's disease.

Bichmann M, Prat Oriol N, Ercan-Herbst E, Schöndorf DC, Gomez Ramos B, Schwärzler V, Neu M, Schlüter A, Wang X, Jin L, Hu C, Tian Y, Ried JS, Haberkant P, Gasparini L, Ehrnhoefer DE. Bichmann M, et al. Among authors: gasparini l. Mol Neurodegener. 2021 Jul 2;16(1):46. doi: 10.1186/s13024-021-00468-x. Mol Neurodegener. 2021. PMID: 34215303 Free PMC article.

4

Tau in the brain interstitial fluid is fragmented and seeding-competent.

Barini E, Plotzky G, Mordashova Y, Hoppe J, Rodriguez-Correa E, Julier S, LePrieult F, Mairhofer I, Mezler M, Biesinger S, Cik M, Meinhardt MW, Ercan-Herbst E, Ehrnhoefer DE, Striebinger A, Bodie K, Klein C, Gasparini L, Schlegel K. Barini E, et al. Among authors: gasparini l. Neurobiol Aging. 2022 Jan;109:64-77. doi: 10.1016/j.neurobiolaging.2021.09.013. Epub 2021 Sep 17. Neurobiol Aging. 2022. PMID: 34655982 Free article.

5

Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates.

Limorenko G, Tatli M, Kolla R, Nazarov S, Weil MT, Schöndorf DC, Geist D, Reinhardt P, Ehrnhoefer DE, Stahlberg H, Gasparini L, Lashuel HA. Limorenko G, et al. Among authors: gasparini l. Nat Commun. 2023 Jul 4;14(1):3939. doi: 10.1038/s41467-023-39314-7. Nat Commun. 2023. PMID: 37402718 Free PMC article.

6

Resting microglia react to Aβ42 fibrils but do not detect oligomers or oligomer-induced neuronal damage.

Ferrera D, Mazzaro N, Canale C, Gasparini L. Ferrera D, et al. Among authors: gasparini l. Neurobiol Aging. 2014 Nov;35(11):2444-2457. doi: 10.1016/j.neurobiolaging.2014.05.023. Epub 2014 May 29. Neurobiol Aging. 2014. PMID: 24973120

7

Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy.

Mazzaro N, Barini E, Spillantini MG, Goedert M, Medini P, Gasparini L. Mazzaro N, et al. Among authors: gasparini l. J Neurosci. 2016 Feb 17;36(7):2086-100. doi: 10.1523/JNEUROSCI.0774-15.2016. J Neurosci. 2016. PMID: 26888921 Free PMC article.

8

Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis.

Mahajani S, Giacomini C, Marinaro F, De Pietri Tonelli D, Contestabile A, Gasparini L. Mahajani S, et al. Among authors: gasparini l. Sci Rep. 2017 Jul 7;7(1):4897. doi: 10.1038/s41598-017-05078-6. Sci Rep. 2017. PMID: 28687747 Free PMC article.

9

Potential roles of insulin and IGF-1 in Alzheimer's disease.

Gasparini L, Xu H. Gasparini L, et al. Trends Neurosci. 2003 Aug;26(8):404-6. doi: 10.1016/S0166-2236(03)00163-2. Trends Neurosci. 2003. PMID: 12900169 Review.

10

Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability.

Gasparini L, Crowther RA, Martin KR, Berg N, Coleman M, Goedert M, Spillantini MG. Gasparini L, et al. Neurobiol Aging. 2011 Mar;32(3):419-33. doi: 10.1016/j.neurobiolaging.2009.03.002. Epub 2009 Apr 7. Neurobiol Aging. 2011. PMID: 19356824

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