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PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Galmozzi A, Kok BP, Kim AS, Montenegro-Burke JR, Lee JY, Spreafico R, Mosure S, Albert V, Cintron-Colon R, Godio C, Webb WR, Conti B, Solt LA, Kojetin D, Parker CG, Peluso JJ, Pru JK, Siuzdak G, Cravatt BF, Saez E. Galmozzi A, et al. Among authors: godio c. Nature. 2019 Dec;576(7785):138-142. doi: 10.1038/s41586-019-1774-2. Epub 2019 Nov 20. Nature. 2019. PMID: 31748741 Free PMC article.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Kok BP, Ghimire S, Kim W, Chatterjee S, Johns T, Kitamura S, Eberhardt J, Ogasawara D, Xu J, Sukiasyan A, Kim SM, Godio C, Bittencourt JM, Cameron M, Galmozzi A, Forli S, Wolan DW, Cravatt BF, Boger DL, Saez E. Kok BP, et al. Among authors: godio c. Nat Chem Biol. 2020 Sep;16(9):997-1005. doi: 10.1038/s41589-020-0555-4. Epub 2020 Jun 8. Nat Chem Biol. 2020. PMID: 32514184 Free PMC article.
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes.
Dominguez E, Galmozzi A, Chang JW, Hsu KL, Pawlak J, Li W, Godio C, Thomas J, Partida D, Niessen S, O'Brien PE, Russell AP, Watt MJ, Nomura DK, Cravatt BF, Saez E. Dominguez E, et al. Among authors: godio c. Nat Chem Biol. 2014 Feb;10(2):113-21. doi: 10.1038/nchembio.1429. Epub 2013 Dec 22. Nat Chem Biol. 2014. PMID: 24362705 Free PMC article.
The Influence of a KDT501, a Novel Isohumulone, on Adipocyte Function in Humans.
Finlin BS, Zhu B, Kok BP, Godio C, Westgate PM, Grayson N, Sims R, Bland JS, Saez E, Kern PA. Finlin BS, et al. Among authors: godio c. Front Endocrinol (Lausanne). 2017 Sep 29;8:255. doi: 10.3389/fendo.2017.00255. eCollection 2017. Front Endocrinol (Lausanne). 2017. PMID: 29033896 Free PMC article.
The nuclear receptor LXR is a glucose sensor.
Mitro N, Mak PA, Vargas L, Godio C, Hampton E, Molteni V, Kreusch A, Saez E. Mitro N, et al. Among authors: godio c. Nature. 2007 Jan 11;445(7124):219-23. doi: 10.1038/nature05449. Epub 2006 Dec 24. Nature. 2007. PMID: 17187055
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Villanueva CJ, Waki H, Godio C, Nielsen R, Chou WL, Vargas L, Wroblewski K, Schmedt C, Chao LC, Boyadjian R, Mandrup S, Hevener A, Saez E, Tontonoz P. Villanueva CJ, et al. Among authors: godio c. Cell Metab. 2011 Apr 6;13(4):413-427. doi: 10.1016/j.cmet.2011.02.014. Cell Metab. 2011. PMID: 21459326 Free PMC article.
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.
Galmozzi A, Mitro N, Ferrari A, Gers E, Gilardi F, Godio C, Cermenati G, Gualerzi A, Donetti E, Rotili D, Valente S, Guerrini U, Caruso D, Mai A, Saez E, De Fabiani E, Crestani M. Galmozzi A, et al. Among authors: godio c. Diabetes. 2013 Mar;62(3):732-42. doi: 10.2337/db12-0548. Epub 2012 Oct 15. Diabetes. 2013. PMID: 23069623 Free PMC article.
Linking epigenetics to lipid metabolism: focus on histone deacetylases.
Ferrari A, Fiorino E, Giudici M, Gilardi F, Galmozzi A, Mitro N, Cermenati G, Godio C, Caruso D, De Fabiani E, Crestani M. Ferrari A, et al. Among authors: godio c. Mol Membr Biol. 2012 Nov;29(7):257-66. doi: 10.3109/09687688.2012.729094. Epub 2012 Oct 24. Mol Membr Biol. 2012. PMID: 23095054 Review.
32 results