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Live Respiratory Syncytial Virus Attenuated by M2-2 Deletion and Stabilized Temperature Sensitivity Mutation 1030s Is a Promising Vaccine Candidate in Children.
McFarland EJ, Karron RA, Muresan P, Cunningham CK, Libous J, Perlowski C, Thumar B, Gnanashanmugam D, Moye J, Schappell E, Barr E, Rexroad V, Fearn L, Spector SA, Aziz M, Cielo M, Beneri C, Wiznia A, Luongo C, Collins P, Buchholz UJ. McFarland EJ, et al. Among authors: collins p. J Infect Dis. 2020 Feb 3;221(4):534-543. doi: 10.1093/infdis/jiz603. J Infect Dis. 2020. PMID: 31758177 Free PMC article. Clinical Trial.
Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.
Connors M, Kulkarni AB, Collins PL, Firestone CY, Holmes KL, Morse HC 3rd, Murphy BR. Connors M, et al. Among authors: collins pl. J Virol. 1992 Feb;66(2):1277-81. doi: 10.1128/JVI.66.2.1277-1281.1992. J Virol. 1992. PMID: 1731105 Free PMC article.
Live viral vaccines for respiratory and enteric tract diseases.
Chanock RM, Murphy BR, Collins PL, Coelingh KV, Olmsted RA, Snyder MH, Spriggs MK, Prince GA, Moss B, Flores J, et al. Chanock RM, et al. Among authors: collins pl. Vaccine. 1988 Apr;6(2):129-33. doi: 10.1016/s0264-410x(88)80014-8. Vaccine. 1988. PMID: 2838984 Review.
2,659 results