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HNF4 Regulates Fatty Acid Oxidation and Is Required for Renewal of Intestinal Stem Cells in Mice.
Gastroenterology. 2020 Mar;158(4):985-999.e9. doi: 10.1053/j.gastro.2019.11.031. Epub 2019 Nov 22.
Gastroenterology. 2020.
PMID: 31759926
Free PMC article.
TFAM is required for maturation of the fetal and adult intestinal epithelium.
Srivillibhuthur M, Warder BN, Toke NH, Shah PP, Feng Q, Gao N, Bonder EM, Verzi MP.
Srivillibhuthur M, et al. Among authors: toke nh.
Dev Biol. 2018 Jul 15;439(2):92-101. doi: 10.1016/j.ydbio.2018.04.015. Epub 2018 Apr 22.
Dev Biol. 2018.
PMID: 29684311
Free PMC article.
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A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity.
Chen L, Toke NH, Luo S, Vasoya RP, Fullem RL, Parthasarathy A, Perekatt AO, Verzi MP.
Chen L, et al. Among authors: toke nh.
Nat Genet. 2019 May;51(5):777-785. doi: 10.1038/s41588-019-0384-0. Epub 2019 Apr 15.
Nat Genet. 2019.
PMID: 30988513
Free PMC article.
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HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine.
Chen L, Toke NH, Luo S, Vasoya RP, Aita R, Parthasarathy A, Tsai YH, Spence JR, Verzi MP.
Chen L, et al. Among authors: toke nh.
Development. 2019 Aug 6;146(19):dev179432. doi: 10.1242/dev.179432.
Development. 2019.
PMID: 31345929
Free PMC article.
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The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac.
Chen L, Luo S, Dupre A, Vasoya RP, Parthasarathy A, Aita R, Malhotra R, Hur J, Toke NH, Chiles E, Yang M, Cao W, Flores J, Ellison CE, Gao N, Sahota A, Su X, Bonder EM, Verzi MP.
Chen L, et al. Among authors: toke nh.
Nat Commun. 2021 May 17;12(1):2886. doi: 10.1038/s41467-021-22761-5.
Nat Commun. 2021.
PMID: 34001900
Free PMC article.
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The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development.
Kumar N, Tsai YH, Chen L, Zhou A, Banerjee KK, Saxena M, Huang S, Toke NH, Xing J, Shivdasani RA, Spence JR, Verzi MP.
Kumar N, et al. Among authors: toke nh.
Development. 2019 Mar 1;146(5):dev172189. doi: 10.1242/dev.172189.
Development. 2019.
PMID: 30745430
Free PMC article.
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Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.
Banerjee KK, Saxena M, Kumar N, Chen L, Cavazza A, Toke NH, O'Neill NK, Madha S, Jadhav U, Verzi MP, Shivdasani RA.
Banerjee KK, et al. Among authors: toke nh.
Genes Dev. 2018 Nov 1;32(21-22):1430-1442. doi: 10.1101/gad.318832.118. Epub 2018 Oct 26.
Genes Dev. 2018.
PMID: 30366903
Free PMC article.
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