Sherman DH - Search Results

1

Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.

Skiba MA, Tran CL, Dan Q, Sikkema AP, Klaver Z, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. Among authors: sherman dh. Structure. 2020 Jan 7;28(1):63-74.e4. doi: 10.1016/j.str.2019.11.004. Epub 2019 Nov 27. Structure. 2020. PMID: 31785925 Free PMC article.

2

The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit.

Chang Z, Flatt P, Gerwick WH, Nguyen VA, Willis CL, Sherman DH. Chang Z, et al. Among authors: sherman dh. Gene. 2002 Aug 21;296(1-2):235-47. doi: 10.1016/s0378-1119(02)00860-0. Gene. 2002. PMID: 12383521

3

Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.

Chang Z, Sitachitta N, Rossi JV, Roberts MA, Flatt PM, Jia J, Sherman DH, Gerwick WH. Chang Z, et al. Among authors: sherman dh. J Nat Prod. 2004 Aug;67(8):1356-67. doi: 10.1021/np0499261. J Nat Prod. 2004. PMID: 15332855

4

Characterization of the initial enzymatic steps of barbamide biosynthesis.

Flatt PM, O'Connell SJ, McPhail KL, Zeller G, Willis CL, Sherman DH, Gerwick WH. Flatt PM, et al. Among authors: sherman dh. J Nat Prod. 2006 Jun;69(6):938-44. doi: 10.1021/np050523q. J Nat Prod. 2006. PMID: 16792414

5

Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair.

Gu L, Jia J, Liu H, Håkansson K, Gerwick WH, Sherman DH. Gu L, et al. Among authors: sherman dh. J Am Chem Soc. 2006 Jul 19;128(28):9014-5. doi: 10.1021/ja0626382. J Am Chem Soc. 2006. PMID: 16834357

6

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Among authors: sherman dh. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

7

Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.

Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA. Giraldes JW, et al. Among authors: sherman dh. Nat Chem Biol. 2006 Oct;2(10):531-6. doi: 10.1038/nchembio822. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969373

8

Clearing the skies over modular polyketide synthases.

Sherman DH, Smith JL. Sherman DH, et al. ACS Chem Biol. 2006 Sep 19;1(8):505-9. doi: 10.1021/cb600376r. ACS Chem Biol. 2006. PMID: 17168537

9

Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching.

Geders TW, Gu L, Mowers JC, Liu H, Gerwick WH, Håkansson K, Sherman DH, Smith JL. Geders TW, et al. Among authors: sherman dh. J Biol Chem. 2007 Dec 7;282(49):35954-63. doi: 10.1074/jbc.M703921200. Epub 2007 Oct 10. J Biol Chem. 2007. PMID: 17928301 Free article.

10

GNAT-like strategy for polyketide chain initiation.

Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. Gu L, et al. Among authors: sherman dh. Science. 2007 Nov 9;318(5852):970-4. doi: 10.1126/science.1148790. Science. 2007. PMID: 17991863

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