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Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints.
Winneroski LL, Erickson JA, Green SJ, Lopez JE, Stout SL, Porter WJ, Timm DE, Audia JE, Barberis M, Beck JP, Boggs LN, Borders AR, Boyer RD, Brier RA, Hembre EJ, Hendle J, Garcia-Losada P, Minguez JM, Mathes BM, May PC, Monk SA, Rankovic Z, Shi Y, Watson BM, Yang Z, Mergott DJ. Winneroski LL, et al. Among authors: green sj. Bioorg Med Chem. 2020 Jan 1;28(1):115194. doi: 10.1016/j.bmc.2019.115194. Epub 2019 Nov 15. Bioorg Med Chem. 2020. PMID: 31786008
Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor.
McKinzie DL, Winneroski LL, Green SJ, Hembre EJ, Erickson JA, Willis BA, Monk SA, Aluise CD, Baker TK, Lopez JE, Hendle J, Beck JP, Brier RA, Boggs LN, Borders AR, Cocke PJ, Garcia-Losada P, Lowe SL, Mathes BM, May PC, Porter WJ, Stout SL, Timm DE, Watson BM, Yang Z, Mergott DJ. McKinzie DL, et al. Among authors: green sj. J Med Chem. 2021 Jun 24;64(12):8076-8100. doi: 10.1021/acs.jmedchem.1c00489. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34081466
Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species.
Willis BA, Lowe SL, Monk SA, Cocke PJ, Aluise CD, Boggs LN, Borders AR, Brier RA, Dean RA, Green SJ, James DE, Jhee SS, Lin Q, Lo AC, May PC, Watson BM, Winneroski LL, Yang Z, Zimmer JA, McKinzie DL, Mergott DJ. Willis BA, et al. Among authors: green sj. J Alzheimers Dis Rep. 2022 Jan 11;6(1):1-15. doi: 10.3233/ADR-210037. eCollection 2022. J Alzheimers Dis Rep. 2022. PMID: 35243208 Free PMC article.
Evidence that the loss of colonic anti-microbial peptides may promote dysbiotic Gram-negative inflammaging-associated bacteria in aging mice.
Forsyth CB, Shaikh M, Engen PA, Preuss F, Naqib A, Palmen BA, Green SJ, Zhang L, Bogin ZR, Lawrence K, Sharma D, Swanson GR, Bishehsari F, Voigt RM, Keshavarzian A. Forsyth CB, et al. Among authors: green sj. Front Aging. 2024 Mar 4;5:1352299. doi: 10.3389/fragi.2024.1352299. eCollection 2024. Front Aging. 2024. PMID: 38501032 Free PMC article.
Topical antibiotics limit depigmentation in a mouse model of vitiligo.
Touni AA, Sohn R, Cosgrove C, Shivde RS, Dellacecca ER, Abdel-Aziz RTA, Cedercreutz K, Green SJ, Abdel-Wahab H, Le Poole IC. Touni AA, et al. Among authors: green sj. Pigment Cell Melanoma Res. 2024 Mar 4. doi: 10.1111/pcmr.13164. Online ahead of print. Pigment Cell Melanoma Res. 2024. PMID: 38439216
Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 in a County Jail.
Adediran T, Zawitz C, Piriani A, Bendict E, Thiede S, Barbian H, Aroutcheva A, Green SJ, Welbel S, Weinstein RA, Snitkin E, Popovich KJ. Adediran T, et al. Among authors: green sj. Open Forum Infect Dis. 2023 Dec 22;11(2):ofad675. doi: 10.1093/ofid/ofad675. eCollection 2024 Feb. Open Forum Infect Dis. 2023. PMID: 38379564 Free PMC article.
Gut microbiota analyses of cutaneous T-cell lymphoma patients undergoing narrowband ultraviolet B therapy reveal alterations associated with disease treatment.
Nguyen WQ, Chrisman LP, Enriquez GL, Hooper MJ, Griffin TL, Ahmad M, Rahman S, Green SJ, Seed PC, Guitart J, Burns MB, Zhou XA. Nguyen WQ, et al. Among authors: green sj. Front Immunol. 2024 Jan 11;14:1280205. doi: 10.3389/fimmu.2023.1280205. eCollection 2023. Front Immunol. 2024. PMID: 38274799 Free PMC article.
Short- and long-term effects of continuous compost amendment on soil microbiome community.
Kraut-Cohen J, Zolti A, Rotbart N, Bar-Tal A, Laor Y, Medina S, Shawahna R, Saadi I, Raviv M, Green SJ, Yermiyahu U, Minz D. Kraut-Cohen J, et al. Among authors: green sj. Comput Struct Biotechnol J. 2023 May 31;21:3280-3292. doi: 10.1016/j.csbj.2023.05.030. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 38213903 Free PMC article.
392 results