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Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis.
Nat Med. 2019 Dec;25(12):1873-1884. doi: 10.1038/s41591-019-0672-3. Epub 2019 Dec 5.
Nat Med. 2019.
PMID: 31806906
Free PMC article.
Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection.
Zimmer B, Ewaleifoh O, Harschnitz O, Lee YS, Peneau C, McAlpine JL, Liu B, Tchieu J, Steinbeck JA, Lafaille F, Volpi S, Notarangelo LD, Casanova JL, Zhang SY, Smith GA, Studer L.
Zimmer B, et al. Among authors: mcalpine jl.
Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8775-E8782. doi: 10.1073/pnas.1809853115. Epub 2018 Aug 28.
Proc Natl Acad Sci U S A. 2018.
PMID: 30154162
Free PMC article.
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TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons.
Gao D, Ciancanelli MJ, Zhang P, Harschnitz O, Bondet V, Hasek M, Chen J, Mu X, Itan Y, Cobat A, Sancho-Shimizu V, Bigio B, Lorenzo L, Ciceri G, McAlpine J, Anguiano E, Jouanguy E, Chaussabel D, Meyts I, Diamond MS, Abel L, Hur S, Smith GA, Notarangelo L, Duffy D, Studer L, Casanova JL, Zhang SY.
Gao D, et al. Among authors: mcalpine j.
J Clin Invest. 2021 Jan 4;131(1):e134529. doi: 10.1172/JCI134529.
J Clin Invest. 2021.
PMID: 33393505
Free PMC article.
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Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development.
Wu HF, Saito-Diaz K, Huang CW, McAlpine JL, Seo DE, Magruder DS, Ishan M, Bergeron HC, Delaney WH, Santori FR, Krishnaswamy S, Hart GW, Chen YW, Hogan RJ, Liu HX, Ivanova NB, Zeltner N.
Wu HF, et al. Among authors: mcalpine jl.
Cell Stem Cell. 2024 May 2;31(5):734-753.e8. doi: 10.1016/j.stem.2024.03.011. Epub 2024 Apr 11.
Cell Stem Cell. 2024.
PMID: 38608707
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