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Targets of the cyclin-dependent kinase Cdk1.
Ubersax JA, Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, Shokat KM, Morgan DO. Ubersax JA, et al. Among authors: shokat km. Nature. 2003 Oct 23;425(6960):859-64. doi: 10.1038/nature02062. Nature. 2003. PMID: 14574415
Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways.
Horiuchi D, Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A. Horiuchi D, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1019-27. doi: 10.1073/pnas.1111317109. Epub 2012 Apr 3. Proc Natl Acad Sci U S A. 2012. PMID: 22474407 Free PMC article.
A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression.
Schachter MM, Merrick KA, Larochelle S, Hirschi A, Zhang C, Shokat KM, Rubin SM, Fisher RP. Schachter MM, et al. Among authors: shokat km. Mol Cell. 2013 Apr 25;50(2):250-60. doi: 10.1016/j.molcel.2013.04.003. Mol Cell. 2013. PMID: 23622515 Free PMC article.
Analog sensitive chemical inhibition of the DEAD-box protein DDX3.
Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA. Floor SN, et al. Among authors: shokat km. Protein Sci. 2016 Mar;25(3):638-49. doi: 10.1002/pro.2857. Epub 2015 Dec 26. Protein Sci. 2016. PMID: 26650549 Free PMC article.
391 results