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Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia.
Somers K, Evans K, Cheung L, Karsa M, Pritchard T, Kosciolek A, Bongers A, El-Ayoubi A, Forgham H, Middlemiss S, Mayoh C, Jones L, Gupta M, Kees UR, Chernova O, Korotchkina L, Gudkov AV, Erickson SW, Teicher B, Smith MA, Norris MD, Haber M, Lock RB, Henderson MJ. Somers K, et al. Among authors: korotchkina l. Leukemia. 2020 Jun;34(6):1524-1539. doi: 10.1038/s41375-019-0683-6. Epub 2019 Dec 17. Leukemia. 2020. PMID: 31848452 Free PMC article.
OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.
Korotchkina L, Kazyulkin D, Komarov PG, Polinsky A, Andrianova EL, Joshi S, Gupta M, Vujcic S, Kononov E, Toshkov I, Tian Y, Krasnov P, Chernov MV, Veith J, Antoch MP, Middlemiss S, Somers K, Lock RB, Norris MD, Henderson MJ, Haber M, Chernova OB, Gudkov AV. Korotchkina L, et al. Leukemia. 2020 Jul;34(7):1828-1839. doi: 10.1038/s41375-019-0692-5. Epub 2020 Jan 2. Leukemia. 2020. PMID: 31896781 Free PMC article.
Paradoxical suppression of cellular senescence by p53.
Demidenko ZN, Korotchkina LG, Gudkov AV, Blagosklonny MV. Demidenko ZN, et al. Among authors: korotchkina lg. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9660-4. doi: 10.1073/pnas.1002298107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457898 Free PMC article.
44 results