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DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.
Van Rompay KKA, Keesler RI, Ardeshir A, Watanabe J, Usachenko J, Singapuri A, Cruzen C, Bliss-Moreau E, Murphy AM, Yee JL, Webster H, Dennis M, Singh T, Heimsath H, Lemos D, Stuart J, Morabito KM, Foreman BM, Burgomaster KE, Noe AT, Dowd KA, Ball E, Woolard K, Presicce P, Kallapur SG, Permar SR, Foulds KE, Coffey LL, Pierson TC, Graham BS. Van Rompay KKA, et al. Sci Transl Med. 2019 Dec 18;11(523):eaay2736. doi: 10.1126/scitranslmed.aay2736. Sci Transl Med. 2019. PMID: 31852797 Free PMC article.
Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV.
Van Rompay KK, Abel K, Lawson JR, Singh RP, Schmidt KA, Evans T, Earl P, Harvey D, Franchini G, Tartaglia J, Montefiori D, Hattangadi S, Moss B, Marthas ML. Van Rompay KK, et al. J Acquir Immune Defic Syndr. 2005 Feb 1;38(2):124-34. doi: 10.1097/00126334-200502010-00002. J Acquir Immune Defic Syndr. 2005. PMID: 15671796
DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge.
Rosati M, Bergamaschi C, Valentin A, Kulkarni V, Jalah R, Alicea C, Patel V, von Gegerfelt AS, Montefiori DC, Venzon DJ, Khan AS, Draghia-Akli R, Van Rompay KK, Felber BK, Pavlakis GN. Rosati M, et al. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15831-6. doi: 10.1073/pnas.0902628106. Epub 2009 Aug 28. Proc Natl Acad Sci U S A. 2009. PMID: 19717425 Free PMC article.
Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus.
von Gegerfelt A, Valentin A, Alicea C, Van Rompay KK, Marthas ML, Montefiori DC, Pavlakis GN, Felber BK. von Gegerfelt A, et al. J Immunol. 2010 Sep 15;185(6):3348-58. doi: 10.4049/jimmunol.1000572. Epub 2010 Aug 11. J Immunol. 2010. PMID: 20702730 Free PMC article.
160 results