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CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance.
Langebäck A, Bacanu S, Laursen H, Mout L, Seki T, Erkens-Schulze S, Ramos AD, Berggren A, Cao Y, Hartman J, van Weerden W, Bergh J, Nordlund P, Lööf S. Langebäck A, et al. Among authors: seki t. Sci Rep. 2019 Dec 18;9(1):19384. doi: 10.1038/s41598-019-55526-8. Sci Rep. 2019. PMID: 31852908 Free PMC article.
Pericyte-fibroblast transition promotes tumor growth and metastasis.
Hosaka K, Yang Y, Seki T, Fischer C, Dubey O, Fredlund E, Hartman J, Religa P, Morikawa H, Ishii Y, Sasahara M, Larsson O, Cossu G, Cao R, Lim S, Cao Y. Hosaka K, et al. Among authors: seki t. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5618-27. doi: 10.1073/pnas.1608384113. Epub 2016 Sep 7. Proc Natl Acad Sci U S A. 2016. PMID: 27608497 Free PMC article.
Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production.
Nakamura M, Zhang Y, Yang Y, Sonmez C, Zheng W, Huang G, Seki T, Iwamoto H, Ding B, Yin L, Foukakis T, Hatschek T, Li X, Hosaka K, Li J, Yu G, Wang X, Liu Y, Cao Y. Nakamura M, et al. Among authors: seki t. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9635-E9644. doi: 10.1073/pnas.1703431114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078273 Free PMC article.
Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.
Iwamoto H, Abe M, Yang Y, Cui D, Seki T, Nakamura M, Hosaka K, Lim S, Wu J, He X, Sun X, Lu Y, Zhou Q, Shi W, Torimura T, Nie G, Li Q, Cao Y. Iwamoto H, et al. Among authors: seki t. Cell Metab. 2018 Jul 3;28(1):104-117.e5. doi: 10.1016/j.cmet.2018.05.005. Epub 2018 May 31. Cell Metab. 2018. PMID: 29861385 Free article.
2,511 results