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Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.
Sci Adv. 2019 Dec 18;5(12):eaax9586. doi: 10.1126/sciadv.aax9586. eCollection 2019 Dec.
Sci Adv. 2019.
PMID: 31897428
Free PMC article.
Clinical Trial.
Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus.
Werth VP, Culton DA, Concha JSS, Graydon JS, Blumberg LJ, Okawa J, Pyzik M, Blumberg RS, Hall RP 3rd.
Werth VP, et al. Among authors: graydon js.
J Invest Dermatol. 2021 Dec;141(12):2858-2865.e4. doi: 10.1016/j.jid.2021.04.031. Epub 2021 Jun 12.
J Invest Dermatol. 2021.
PMID: 34126109
Free article.
Clinical Trial.
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Ethnogeographic prevalence and implications of the 677C>T and 1298A>C MTHFR polymorphisms in US primary care populations.
Graydon JS, Claudio K, Baker S, Kocherla M, Ferreira M, Roche-Lima A, Rodríguez-Maldonado J, Duconge J, Ruaño G.
Graydon JS, et al.
Biomark Med. 2019 Jun;13(8):649-661. doi: 10.2217/bmm-2018-0392. Epub 2019 Jun 3.
Biomark Med. 2019.
PMID: 31157538
Free PMC article.
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Complications of Psychotropic and Pain Medications in an Ultrarapid Metabolizer Patient at the Upper 1% of Cytochrome P450 (CYP450) Function Quantified by Combinatorial CYP450 Genotyping.
Ruaño G, Larsen K, Kocherla M, Graydon JS, Kost J.
Ruaño G, et al. Among authors: graydon js.
J Pain Palliat Care Pharmacother. 2017 Jun;31(2):126-138. doi: 10.1080/15360288.2017.1304494. Epub 2017 May 16.
J Pain Palliat Care Pharmacother. 2017.
PMID: 28506184
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Practical interpretation of CYP2D6 haplotypes: Comparison and integration of automated and expert calling.
Ruaño G, Kocherla M, Graydon JS, Holford TR, Makowski GS, Goethe JW.
Ruaño G, et al. Among authors: graydon js.
Clin Chim Acta. 2016 May 1;456:7-14. doi: 10.1016/j.cca.2016.02.011. Epub 2016 Feb 18.
Clin Chim Acta. 2016.
PMID: 26908082
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A collaborative genetical survey in Marshall islanders.
SIMMONS RT, GRAYDON JS, SEMPLE NM, BIRDSELL JB, MILBOURNE JD, LEE JR.
SIMMONS RT, et al. Among authors: graydon js.
Am J Phys Anthropol. 1952 Mar;10(1):31-54. doi: 10.1002/ajpa.1330100117.
Am J Phys Anthropol. 1952.
PMID: 14923846
No abstract available.
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