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Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.
Blumberg LJ, Humphries JE, Jones SD, Pearce LB, Holgate R, Hearn A, Cheung J, Mahmood A, Del Tito B, Graydon JS, Stolz LE, Bitonti A, Purohit S, de Graaf D, Kacena K, Andersen JT, Christianson GJ, Roopenian DC, Hubbard JJ, Gandhi AK, Lasseter K, Pyzik M, Blumberg RS. Blumberg LJ, et al. Among authors: hearn a. Sci Adv. 2019 Dec 18;5(12):eaax9586. doi: 10.1126/sciadv.aax9586. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31897428 Free PMC article. Clinical Trial.
Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein.
Munoz Pinto MF, Campbell SJ, Simoglou Karali C, Johanssen VA, Bristow C, Cheng VWT, Zarghami N, Larkin JR, Pannell M, Hearn A, Chui C, Brinquis Nunez B, Bokma E, Holgate R, Anthony DC, Sibson NR. Munoz Pinto MF, et al. Among authors: hearn a. Neuro Oncol. 2022 Jan 5;24(1):52-63. doi: 10.1093/neuonc/noab177. Neuro Oncol. 2022. PMID: 34297105 Free PMC article.
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
Widjaja AA, Dong J, Adami E, Viswanathan S, Ng B, Pakkiri LS, Chothani SP, Singh BK, Lim WW, Zhou J, Shekeran SG, Tan J, Lim SY, Goh J, Wang M, Holgate R, Hearn A, Felkin LE, Yen PM, Dear JW, Drum CL, Schafer S, Cook SA. Widjaja AA, et al. Among authors: hearn a. Sci Transl Med. 2021 Jun 9;13(597):eaba8146. doi: 10.1126/scitranslmed.aba8146. Sci Transl Med. 2021. PMID: 34108253
Preserved antibody responses to COVID-19 vaccination and lower odds of developing COVID-19 in adults with severe asthma.
Rupani H, Edwards D, Chaudhuri R, Smith S, Jackson DJ, Hearn A, Richards J, Moyses H, Kurukulaaratchy RJ, Haitchi HM, Edwards MR, Johnston SL, Djukanovic R. Rupani H, et al. Among authors: hearn a. J Allergy Clin Immunol Pract. 2024 May 23:S2213-2198(24)00540-3. doi: 10.1016/j.jaip.2024.05.026. Online ahead of print. J Allergy Clin Immunol Pract. 2024. PMID: 38796102 Free article. No abstract available.
Identifying priority sites for whale shark ship collision management globally.
Womersley FC, Rohner CA, Abrantes K, Afonso P, Arunrugstichai S, Bach SS, Bar S, Barash A, Barnes P, Barnett A, Boldrocchi G, Buffat N, Canon T, Perez CC, Chuangcharoendee M, Cochran JEM, de la Parra R, Diamant S, Driggers W, Dudgeon CL, Erdmann MV, Fitzpatrick R, Flam A, Fontes J, Francis G, Galvan BE, Graham RT, Green SM, Green JR, Grosmark Y, Guzman HM, Hardenstine RS, Harvey M, Harvey-Carroll J, Hasan AW, Hearn AR, Hendon JM, Putra MIH, Himawan MR, Hoffmayer E, Holmberg J, Hsu HH, Jaidah MY, Jansen A, Judd C, Kuguru B, Lester E, Macena BCL, Magson K, Maguiño R, Manjaji-Matsumoto M, Marcoux SD, Marcoux T, McKinney J, Meekan M, Mendoza A, Moazzam M, Monacella E, Norman B, Perry C, Pierce S, Prebble C, Macías DR, Raudino H, Reynolds S, Robinson D, Rowat D, Santos MD, Schmidt J, Scott C, See ST, Sianipar A, Speed CW, Syakurachman I, Tyne JA, Waples K, Winn C, Yuneni RR, Zareer I, Araujo G. Womersley FC, et al. Among authors: hearn ar. Sci Total Environ. 2024 Jul 15;934:172776. doi: 10.1016/j.scitotenv.2024.172776. Epub 2024 May 1. Sci Total Environ. 2024. PMID: 38697520 Free article.
CamTrapAsia: A dataset of tropical forest vertebrate communities from 239 camera trapping studies.
Mendes CP, Albert WR, Amir Z, Ancrenaz M, Ash E, Azhar B, Bernard H, Brodie J, Bruce T, Carr E, Clements GR, Davies G, Deere NJ, Dinata Y, Donnelly CA, Duangchantrasiri S, Fredriksson G, Goossens B, Granados A, Hearn A, Hon J, Hughes T, Jansen P, Kawanishi K, Kinnaird M, Koh S, Latinne A, Linkie M, Loi F, Lynam AJ, Meijaard E, Mohd-Azlan J, Moore JH, Nathan SKSS, Ngoprasert D, Novarino W, Nursamsi I, O'Brien T, Ong R, Payne J, Priatna D, Rayan DM, Reynolds G, Rustam R, Selvadurai S, Shia A, Silmi M, Sinovas P, Sribuarod K, Steinmetz R, Struebig MJ, Sukmasuang R, Sunarto S, Tarmizi T, Thapa A, Traeholt C, Wearn OR, Wibisono HB, Wilting A, Wong ST, Wong ST, Word J, Chiok WX, Zainuddin ZZ, Luskin MS. Mendes CP, et al. Among authors: hearn a. Ecology. 2024 Jun;105(6):e4299. doi: 10.1002/ecy.4299. Epub 2024 Apr 22. Ecology. 2024. PMID: 38650359
Long-Term Effectiveness of Anti-IL-4R Therapy Following Suboptimal Response to Anti-IL-5/5R Therapy in Severe Eosinophilic Asthma.
Gates J, Hearn A, Mason T, Fernandes M, Green L, Thomson L, Roxas C, Lam J, d'Ancona G, Nanzer AM, Dhariwal J, Jackson DJ. Gates J, et al. Among authors: hearn a. J Allergy Clin Immunol Pract. 2024 Apr 5:S2213-2198(24)00343-X. doi: 10.1016/j.jaip.2024.03.049. Online ahead of print. J Allergy Clin Immunol Pract. 2024. PMID: 38583517
128 results