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Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity.
Shapiro MB, Cheever T, Malherbe DC, Pandey S, Reed J, Yang ES, Wang K, Pegu A, Chen X, Siess D, Burke D, Henderson H, Lewinsohn R, Fischer M, Stanton JJ, Axthelm MK, Kahl C, Park B, Lewis AD, Sacha JB, Mascola JR, Hessell AJ, Haigwood NL. Shapiro MB, et al. Among authors: hessell aj. Nat Commun. 2020 Jan 7;11(1):70. doi: 10.1038/s41467-019-13972-y. Nat Commun. 2020. PMID: 31911610 Free PMC article.
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Chen L, Kwon YD, Zhou T, Wu X, O'Dell S, Cavacini L, Hessell AJ, Pancera M, Tang M, Xu L, Yang ZY, Zhang MY, Arthos J, Burton DR, Dimitrov DS, Nabel GJ, Posner MR, Sodroski J, Wyatt R, Mascola JR, Kwong PD. Chen L, et al. Among authors: hessell aj. Science. 2009 Nov 20;326(5956):1123-7. doi: 10.1126/science.1175868. Science. 2009. PMID: 19965434 Free PMC article.
Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques.
Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, Guo B, Reed JS, Leon EJ, Engelmann F, Zheng B, Legasse A, Park B, Dickerson M, Lewis AD, Colgin LM, Axthelm M, Messaoudi I, Sacha JB, Burton DR, Forthal DN, Hessell AJ, Haigwood NL. Jaworski JP, et al. Among authors: hessell aj. J Virol. 2013 Oct;87(19):10447-59. doi: 10.1128/JVI.00049-13. Epub 2013 Jul 24. J Virol. 2013. PMID: 23885083 Free PMC article.
Emergence of broadly neutralizing antibodies and viral coevolution in two subjects during the early stages of infection with human immunodeficiency virus type 1.
Sather DN, Carbonetti S, Malherbe DC, Pissani F, Stuart AB, Hessell AJ, Gray MD, Mikell I, Kalams SA, Haigwood NL, Stamatatos L. Sather DN, et al. Among authors: hessell aj. J Virol. 2014 Nov;88(22):12968-81. doi: 10.1128/JVI.01816-14. Epub 2014 Aug 13. J Virol. 2014. PMID: 25122781 Free PMC article.
Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.
Malherbe DC, Pissani F, Sather DN, Guo B, Pandey S, Sutton WF, Stuart AB, Robins H, Park B, Krebs SJ, Schuman JT, Kalams S, Hessell AJ, Haigwood NL. Malherbe DC, et al. Among authors: hessell aj. J Virol. 2014 Nov;88(22):12949-67. doi: 10.1128/JVI.01812-14. Epub 2014 Sep 10. J Virol. 2014. PMID: 25210191 Free PMC article.
Animal models in HIV-1 protection and therapy.
Hessell AJ, Haigwood NL. Hessell AJ, et al. Curr Opin HIV AIDS. 2015 May;10(3):170-6. doi: 10.1097/COH.0000000000000152. Curr Opin HIV AIDS. 2015. PMID: 25730345 Free PMC article. Review.
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