Gao Q - Search Results

1

Design, Synthesis, and Evaluation of Novel Enterovirus 71 Inhibitors as Therapeutic Drug Leads for the Treatment of Human Hand, Foot, and Mouth Disease.

Zhang M, Wang Y, He W, Sun Y, Guo Y, Zhong W, Gao Q, Liao M, Wang X, Cai Y, Guo Y, Rao Z. Zhang M, et al. Among authors: gao q. J Med Chem. 2020 Feb 13;63(3):1233-1244. doi: 10.1021/acs.jmedchem.9b01414. Epub 2020 Jan 29. J Med Chem. 2020. PMID: 31939669

2

Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71.

Zhu L, Xu K, Wang N, Cao L, Wu J, Gao Q, Fry EE, Stuart DI, Rao Z, Wang J, Wang X. Zhu L, et al. Among authors: gao q. mBio. 2018 Jul 3;9(4):e01013-18. doi: 10.1128/mBio.01013-18. mBio. 2018. PMID: 29970466 Free PMC article.

3

Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.

Zhu L, Sun Y, Fan J, Zhu B, Cao L, Gao Q, Zhang Y, Liu H, Rao Z, Wang X. Zhu L, et al. Among authors: gao q. Nat Commun. 2018 Nov 26;9(1):4985. doi: 10.1038/s41467-018-07531-0. Nat Commun. 2018. PMID: 30478256 Free PMC article.

4

Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.

Cao L, Liu P, Yang P, Gao Q, Li H, Sun Y, Zhu L, Lin J, Su D, Rao Z, Wang X. Cao L, et al. Among authors: gao q. PLoS Biol. 2019 Apr 30;17(4):e3000229. doi: 10.1371/journal.pbio.3000229. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 31039149 Free PMC article.

5

Cryo-EM structure of a herpesvirus capsid at 3.1 Å.

Yuan S, Wang J, Zhu D, Wang N, Gao Q, Chen W, Tang H, Wang J, Zhang X, Liu H, Rao Z, Wang X. Yuan S, et al. Among authors: gao q. Science. 2018 Apr 6;360(6384):eaao7283. doi: 10.1126/science.aao7283. Science. 2018. PMID: 29622627

6

Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies.

Qiu X, Lei Y, Yang P, Gao Q, Wang N, Cao L, Yuan S, Huang X, Deng Y, Ma W, Ding T, Zhang F, Wu X, Hu J, Liu SL, Qin C, Wang X, Xu Z, Rao Z. Qiu X, et al. Among authors: gao q. Nat Microbiol. 2018 Mar;3(3):287-294. doi: 10.1038/s41564-017-0099-x. Epub 2018 Jan 29. Nat Microbiol. 2018. PMID: 29379207

7

Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component.

Wang J, Yuan S, Zhu D, Tang H, Wang N, Chen W, Gao Q, Li Y, Wang J, Liu H, Zhang X, Rao Z, Wang X. Wang J, et al. Among authors: gao q. Nat Commun. 2018 Sep 10;9(1):3668. doi: 10.1038/s41467-018-06078-4. Nat Commun. 2018. PMID: 30201968 Free PMC article.

8

Identification of (6S)-cyclopropyl-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxamines as new HBV capsid assembly modulators.

Lv K, Wu S, Tao Z, Wang A, Xu S, Yang L, Gao Q, Wang A, Qin X, Jiang B, Wu W, Jia X, Li Y, Jiang J, Liu M. Lv K, et al. Among authors: gao q. Eur J Med Chem. 2022 Jan 15;228:113974. doi: 10.1016/j.ejmech.2021.113974. Epub 2021 Nov 6. Eur J Med Chem. 2022. PMID: 34772528

9

Picornavirus uncoating intermediate captured in atomic detail.

Ren J, Wang X, Hu Z, Gao Q, Sun Y, Li X, Porta C, Walter TS, Gilbert RJ, Zhao Y, Axford D, Williams M, McAuley K, Rowlands DJ, Yin W, Wang J, Stuart DI, Rao Z, Fry EE. Ren J, et al. Among authors: gao q. Nat Commun. 2013;4:1929. doi: 10.1038/ncomms2889. Nat Commun. 2013. PMID: 23728514 Free PMC article.

10

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial.

Zhang Y, Zeng G, Pan H, Li C, Hu Y, Chu K, Han W, Chen Z, Tang R, Yin W, Chen X, Hu Y, Liu X, Jiang C, Li J, Yang M, Song Y, Wang X, Gao Q, Zhu F. Zhang Y, et al. Among authors: gao q. Lancet Infect Dis. 2021 Feb;21(2):181-192. doi: 10.1016/S1473-3099(20)30843-4. Epub 2020 Nov 17. Lancet Infect Dis. 2021. PMID: 33217362 Free PMC article. Clinical Trial.

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