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A framework for advancing our understanding of cancer-associated fibroblasts.
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. Sahai E, et al. Among authors: denardo dg. Nat Rev Cancer. 2020 Mar;20(3):174-186. doi: 10.1038/s41568-019-0238-1. Epub 2020 Jan 24. Nat Rev Cancer. 2020. PMID: 31980749 Free PMC article. Review.
Targeting tumor-infiltrating macrophages to combat cancer.
Panni RZ, Linehan DC, DeNardo DG. Panni RZ, et al. Among authors: denardo dg. Immunotherapy. 2013 Oct;5(10):1075-87. doi: 10.2217/imt.13.102. Immunotherapy. 2013. PMID: 24088077 Free PMC article. Review.
Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic.
Ohman KA, Hashim YM, Vangveravong S, Nywening TM, Cullinan DR, Goedegebuure SP, Liu J, Van Tine BA, Tiriac H, Tuveson DA, DeNardo DG, Spitzer D, Mach RH, Hawkins WG. Ohman KA, et al. Among authors: denardo dg. Oncotarget. 2016 Jun 7;7(23):33529-41. doi: 10.18632/oncotarget.9551. Oncotarget. 2016. PMID: 27244881 Free PMC article.
Senescent CAFs mediate immunosuppression and drive breast cancer progression.
Ye J, Baer JM, Faget DV, Morikis VA, Ren Q, Melam A, Delgado AP, Luo X, Mullick Bagchi S, Belle JI, Campos E, Friedman M, Veis DJ, Knudsen ES, Witkiewicz AK, Powers S, Longmore GD, DeNardo DG, Stewart SA. Ye J, et al. Among authors: denardo dg. Cancer Discov. 2024 Apr 29. doi: 10.1158/2159-8290.CD-23-0426. Online ahead of print. Cancer Discov. 2024. PMID: 38683161
Immune cells as mediators of solid tumor metastasis.
DeNardo DG, Johansson M, Coussens LM. DeNardo DG, et al. Cancer Metastasis Rev. 2008 Mar;27(1):11-8. doi: 10.1007/s10555-007-9100-0. Cancer Metastasis Rev. 2008. PMID: 18066650 Review.
107 results