Ferretti GDS - Search Results

1

Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers.

Pedrote MM, Motta MF, Ferretti GDS, Norberto DR, Spohr TCLS, Lima FRS, Gratton E, Silva JL, de Oliveira GAP. Pedrote MM, et al. Among authors: ferretti gds. iScience. 2020 Feb 21;23(2):100820. doi: 10.1016/j.isci.2020.100820. Epub 2020 Jan 8. iScience. 2020. PMID: 31981923 Free PMC article.

2

Moniliophthora perniciosa necrosis- and ethylene-inducing protein 2 (MpNep2) as a metastable dimer in solution: structural and functional implications.

de Oliveira GA, Pereira EG, Dias CV, Souza TL, Ferretti GD, Cordeiro Y, Camillo LR, Cascardo J, Almeida FC, Valente AP, Silva JL. de Oliveira GA, et al. PLoS One. 2012;7(9):e45620. doi: 10.1371/journal.pone.0045620. Epub 2012 Sep 24. PLoS One. 2012. PMID: 23029140 Free PMC article.

3

Intramolecular dynamics within the N-Cap-SH3-SH2 regulatory unit of the c-Abl tyrosine kinase reveal targeting to the cellular membrane.

de Oliveira GA, Pereira EG, Ferretti GD, Valente AP, Cordeiro Y, Silva JL. de Oliveira GA, et al. J Biol Chem. 2013 Sep 27;288(39):28331-45. doi: 10.1074/jbc.M113.500926. Epub 2013 Aug 8. J Biol Chem. 2013. PMID: 23928308 Free PMC article.

4

Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex.

Beraldo FH, Ostapchenko VG, Caetano FA, Guimaraes AL, Ferretti GD, Daude N, Bertram L, Nogueira KO, Silva JL, Westaway D, Cashman NR, Martins VR, Prado VF, Prado MA. Beraldo FH, et al. J Biol Chem. 2016 Oct 14;291(42):21945-21955. doi: 10.1074/jbc.M116.738286. Epub 2016 Aug 25. J Biol Chem. 2016. PMID: 27563063 Free PMC article.

5

p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells.

Rangel LP, Ferretti GDS, Costa CL, Andrade SMMV, Carvalho RS, Costa DCF, Silva JL. Rangel LP, et al. Among authors: ferretti gds. J Biol Chem. 2019 Mar 8;294(10):3670-3682. doi: 10.1074/jbc.RA118.004671. Epub 2019 Jan 2. J Biol Chem. 2019. PMID: 30602570 Free PMC article.

6

Recent Synthetic Approaches towards Small Molecule Reactivators of p53.

Silva JL, Lima CGS, Rangel LP, Ferretti GDS, Pauli FP, Ribeiro RCB, da Silva TB, da Silva FC, Ferreira VF. Silva JL, et al. Among authors: ferretti gds. Biomolecules. 2020 Apr 20;10(4):635. doi: 10.3390/biom10040635. Biomolecules. 2020. PMID: 32326087 Free PMC article. Review.

7

Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.

Petronilho EC, Pedrote MM, Marques MA, Passos YM, Mota MF, Jakobus B, de Sousa GDS, Pereira da Costa F, Felix AL, Ferretti GDS, Almeida FP, Cordeiro Y, Vieira TCRG, de Oliveira GAP, Silva JL. Petronilho EC, et al. Among authors: ferretti gds. Chem Sci. 2021 Apr 26;12(21):7334-7349. doi: 10.1039/d1sc01739j. Chem Sci. 2021. PMID: 34163823 Free PMC article.

8

Anticancer Therapeutic Strategies Targeting p53 Aggregation.

Ferretti GDS, Quarti J, Dos Santos G, Rangel LP, Silva JL. Ferretti GDS, et al. Int J Mol Sci. 2022 Sep 20;23(19):11023. doi: 10.3390/ijms231911023. Int J Mol Sci. 2022. PMID: 36232329 Free PMC article. Review.

9

PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma.

Paz MM, Ferretti GDS, Martins-Dinis MMC, Ferreira BIS, Faier-Pereira A, Barnoud T, Moreira OC, Silva JL, Cordeiro Y, Rangel LP. Paz MM, et al. Among authors: ferretti gds. Front Mol Biosci. 2023 Apr 10;10:1165132. doi: 10.3389/fmolb.2023.1165132. eCollection 2023. Front Mol Biosci. 2023. PMID: 37101558 Free PMC article.

10

Targeting Biomolecular Condensation and Protein Aggregation against Cancer.

Silva JL, Foguel D, Ferreira VF, Vieira TCRG, Marques MA, Ferretti GDS, Outeiro TF, Cordeiro Y, de Oliveira GAP. Silva JL, et al. Among authors: ferretti gds. Chem Rev. 2023 Jul 26;123(14):9094-9138. doi: 10.1021/acs.chemrev.3c00131. Epub 2023 Jun 28. Chem Rev. 2023. PMID: 37379327 Review.

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