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Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer.
Pedrote MM, de Oliveira GAP, Felix AL, Mota MF, Marques MA, Soares IN, Iqbal A, Norberto DR, Gomes AMO, Gratton E, Cino EA, Silva JL. Pedrote MM, et al. Among authors: norberto dr. J Biol Chem. 2018 Jul 20;293(29):11374-11387. doi: 10.1074/jbc.RA118.003285. Epub 2018 May 31. J Biol Chem. 2018. PMID: 29853637 Free PMC article.
Cavities determine the pressure unfolding of proteins.
Roche J, Caro JA, Norberto DR, Barthe P, Roumestand C, Schlessman JL, Garcia AE, García-Moreno BE, Royer CA. Roche J, et al. Among authors: norberto dr. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6945-50. doi: 10.1073/pnas.1200915109. Epub 2012 Apr 10. Proc Natl Acad Sci U S A. 2012. PMID: 22496593 Free PMC article.