Laperle AH - Search Results

1

iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates.

Laperle AH, Sances S, Yucer N, Dardov VJ, Garcia VJ, Ho R, Fulton AN, Jones MR, Roxas KM, Avalos P, West D, Banuelos MG, Shu Z, Murali R, Maidment NT, Van Eyk JE, Tagliati M, Svendsen CN. Laperle AH, et al. Nat Med. 2020 Feb;26(2):289-299. doi: 10.1038/s41591-019-0739-1. Epub 2020 Jan 27. Nat Med. 2020. PMID: 31988461

2

Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.

Sances S, Ho R, Vatine G, West D, Laperle A, Meyer A, Godoy M, Kay PS, Mandefro B, Hatata S, Hinojosa C, Wen N, Sareen D, Hamilton GA, Svendsen CN. Sances S, et al. Stem Cell Reports. 2018 Apr 10;10(4):1222-1236. doi: 10.1016/j.stemcr.2018.02.012. Epub 2018 Mar 22. Stem Cell Reports. 2018. PMID: 29576540 Free PMC article.

3

Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis.

Yucer N, Ahdoot R, Workman MJ, Laperle AH, Recouvreux MS, Kurowski K, Naboulsi DJ, Liang V, Qu Y, Plummer JT, Gayther SA, Orsulic S, Karlan BY, Svendsen CN. Yucer N, et al. Among authors: laperle ah. Cell Rep. 2021 Dec 28;37(13):110146. doi: 10.1016/j.celrep.2021.110146. Cell Rep. 2021. PMID: 34965417 Free PMC article.

4

The proSAAS Chaperone Provides Neuroprotection and Attenuates Transsynaptic α-Synuclein Spread in Rodent Models of Parkinson's Disease.

Lindberg I, Shu Z, Lam H, Helwig M, Yucer N, Laperle A, Svendsen CN, Di Monte DA, Maidment NT. Lindberg I, et al. J Parkinsons Dis. 2022;12(5):1463-1478. doi: 10.3233/JPD-213053. J Parkinsons Dis. 2022. PMID: 35527562 Free PMC article.

5

Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration.

Laperle AH, Moser VA, Avalos P, Lu B, Wu A, Fulton A, Ramirez S, Garcia VJ, Bell S, Ho R, Lawless G, Roxas K, Shahin S, Shelest O, Svendsen S, Wang S, Svendsen CN. Laperle AH, et al. Stem Cell Reports. 2023 Aug 8;18(8):1629-1642. doi: 10.1016/j.stemcr.2023.03.016. Epub 2023 Apr 20. Stem Cell Reports. 2023. PMID: 37084724 Free PMC article.

6

Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons.

Otero MG, Bell S, Laperle AH, Lawless G, Myers Z, Castro MA, Villalba JM, Svendsen CN. Otero MG, et al. Among authors: laperle ah. Int J Mol Sci. 2023 Sep 18;24(18):14227. doi: 10.3390/ijms241814227. Int J Mol Sci. 2023. PMID: 37762529 Free PMC article.

7

Human Neural Progenitors Expressing GDNF Enhance Retinal Protection in a Rodent Model of Retinal Degeneration.

Shahin S, Tan P, Chetsawang J, Lu B, Svendsen S, Ramirez S, Conniff T, Alfaro JS, Fernandez M, Fulton A, Laperle AH, Svendsen CN, Wang S. Shahin S, et al. Among authors: laperle ah. Stem Cells Transl Med. 2023 Nov 3;12(11):727-744. doi: 10.1093/stcltm/szad054. Stem Cells Transl Med. 2023. PMID: 37786347 Free PMC article.

8

Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells.

Mozneb M, Jenkins A, Sances S, Pohlman S, Workman MJ, West D, Ondatje B, El-Ghazawi K, Woodbury A, Garcia VJ, Patel S, Arzt M, Dezem F, Laperle AH, Moser VA, Ho R, Yucer N, Plummer J, Barrett RJ, Svendsen CN, Sharma A. Mozneb M, et al. Among authors: laperle ah. Lab Chip. 2024 Feb 13;24(4):869-881. doi: 10.1039/d3lc00745f. Lab Chip. 2024. PMID: 38252454

9

α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal.

Laperle A, Hsiao C, Lampe M, Mortier J, Saha K, Palecek SP, Masters KS. Laperle A, et al. Stem Cell Reports. 2015 Aug 11;5(2):195-206. doi: 10.1016/j.stemcr.2015.06.009. Epub 2015 Jul 30. Stem Cell Reports. 2015. PMID: 26235893 Free PMC article.

10

Influence of substrate composition on human embryonic stem cell differentiation and extracellular matrix production in embryoid bodies.

Laperle A, Masters KS, Palecek SP. Laperle A, et al. Biotechnol Prog. 2015 Jan-Feb;31(1):212-9. doi: 10.1002/btpr.2001. Epub 2014 Oct 28. Biotechnol Prog. 2015. PMID: 25311359 Free PMC article.

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