Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

140 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates.
Laperle AH, Sances S, Yucer N, Dardov VJ, Garcia VJ, Ho R, Fulton AN, Jones MR, Roxas KM, Avalos P, West D, Banuelos MG, Shu Z, Murali R, Maidment NT, Van Eyk JE, Tagliati M, Svendsen CN. Laperle AH, et al. Among authors: maidment nt. Nat Med. 2020 Feb;26(2):289-299. doi: 10.1038/s41591-019-0739-1. Epub 2020 Jan 27. Nat Med. 2020. PMID: 31988461
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease.
Fitzmaurice AG, Rhodes SL, Lulla A, Murphy NP, Lam HA, O'Donnell KC, Barnhill L, Casida JE, Cockburn M, Sagasti A, Stahl MC, Maidment NT, Ritz B, Bronstein JM. Fitzmaurice AG, et al. Among authors: maidment nt. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):636-41. doi: 10.1073/pnas.1220399110. Epub 2012 Dec 24. Proc Natl Acad Sci U S A. 2013. PMID: 23267077 Free PMC article.
Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein.
Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. Lam HA, et al. Among authors: maidment nt. J Neurosci Res. 2011 Jul;89(7):1091-102. doi: 10.1002/jnr.22611. Epub 2011 Apr 12. J Neurosci Res. 2011. PMID: 21488084 Free PMC article.
Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Lu XH, et al. Among authors: maidment nt. J Neurosci. 2009 Feb 18;29(7):1962-76. doi: 10.1523/JNEUROSCI.5351-08.2009. J Neurosci. 2009. PMID: 19228951 Free PMC article.
Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward.
Cui Y, Ostlund SB, James AS, Park CS, Ge W, Roberts KW, Mittal N, Murphy NP, Cepeda C, Kieffer BL, Levine MS, Jentsch JD, Walwyn WM, Sun YE, Evans CJ, Maidment NT, Yang XW. Cui Y, et al. Among authors: maidment nt. Nat Neurosci. 2014 Feb;17(2):254-61. doi: 10.1038/nn.3622. Epub 2014 Jan 12. Nat Neurosci. 2014. PMID: 24413699 Free PMC article.
The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity.
Jarvela TS, Lam HA, Helwig M, Lorenzen N, Otzen DE, McLean PJ, Maidment NT, Lindberg I. Jarvela TS, et al. Among authors: maidment nt. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4708-15. doi: 10.1073/pnas.1601091113. Epub 2016 Jul 25. Proc Natl Acad Sci U S A. 2016. PMID: 27457957 Free PMC article.
Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice.
Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. Richter F, et al. Among authors: maidment nt. Neurobiol Aging. 2017 Mar;51:54-66. doi: 10.1016/j.neurobiolaging.2016.11.015. Epub 2016 Dec 1. Neurobiol Aging. 2017. PMID: 28038352 Free PMC article.
Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression.
Lawal HO, Terrell A, Lam HA, Djapri C, Jang J, Hadi R, Roberts L, Shahi V, Chou MT, Biedermann T, Huang B, Lawless GM, Maidment NT, Krantz DE. Lawal HO, et al. Among authors: maidment nt. Mol Psychiatry. 2014 Feb;19(2):235-42. doi: 10.1038/mp.2012.170. Epub 2012 Dec 11. Mol Psychiatry. 2014. PMID: 23229049 Free PMC article.
140 results