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Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Schommers P, Gruell H, Abernathy ME, Tran MK, Dingens AS, Gristick HB, Barnes CO, Schoofs T, Schlotz M, Vanshylla K, Kreer C, Weiland D, Holtick U, Scheid C, Valter MM, van Gils MJ, Sanders RW, Vehreschild JJ, Cornely OA, Lehmann C, Fätkenheuer G, Seaman MS, Bloom JD, Bjorkman PJ, Klein F. Schommers P, et al. Among authors: sanders rw. Cell. 2020 Feb 6;180(3):471-489.e22. doi: 10.1016/j.cell.2020.01.010. Epub 2020 Jan 30. Cell. 2020. PMID: 32004464 Free PMC article.
Inhibition of HIV-1 by fusion inhibitors.
Eggink D, Berkhout B, Sanders RW. Eggink D, et al. Among authors: sanders rw. Curr Pharm Des. 2010;16(33):3716-28. doi: 10.2174/138161210794079218. Curr Pharm Des. 2010. PMID: 21128887 Review.
HIV takes double hit before entry.
Sanders RW. Sanders RW. BMC Biol. 2013 Dec 7;10:99. doi: 10.1186/1741-7007-10-99. BMC Biol. 2013. PMID: 23216951 Free PMC article.
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.
Julien JP, Lee JH, Cupo A, Murin CD, Derking R, Hoffenberg S, Caulfield MJ, King CR, Marozsan AJ, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Julien JP, et al. Among authors: sanders rw. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4351-6. doi: 10.1073/pnas.1217537110. Epub 2013 Feb 20. Proc Natl Acad Sci U S A. 2013. PMID: 23426631 Free PMC article.
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, Burton DR, Poignard P, Ward AB, Wilson IA. Julien JP, et al. Among authors: sanders rw. PLoS Pathog. 2013;9(5):e1003342. doi: 10.1371/journal.ppat.1003342. Epub 2013 May 2. PLoS Pathog. 2013. PMID: 23658524 Free PMC article.
435 results