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Detection of Biologically Relevant Low-Titer Neutralizing Antibodies Against Adeno-Associated Virus Require Sensitive In Vitro Assays.
Kruzik A, Koppensteiner H, Fetahagic D, Hartlieb B, Dorn S, Romeder-Finger S, Coulibaly S, Weber A, Hoellriegl W, Horling FM, Scheiflinger F, Reipert BM, de la Rosa M. Kruzik A, et al. Among authors: de la rosa m. Hum Gene Ther Methods. 2019 Apr;30(2):35-43. doi: 10.1089/hgtb.2018.263. Epub 2019 Mar 29. Hum Gene Ther Methods. 2019. PMID: 30734588
BAX 335 hemophilia B gene therapy clinical trial results: potential impact of CpG sequences on gene expression.
Konkle BA, Walsh CE, Escobar MA, Josephson NC, Young G, von Drygalski A, McPhee SWJ, Samulski RJ, Bilic I, de la Rosa M, Reipert BM, Rottensteiner H, Scheiflinger F, Chapin JC, Ewenstein B, Monahan PE. Konkle BA, et al. Among authors: de la rosa m. Blood. 2021 Feb 11;137(6):763-774. doi: 10.1182/blood.2019004625. Blood. 2021. PMID: 33067633 Free PMC article. Clinical Trial.
Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency.
Cao W, Dong B, Horling F, Firrman JA, Lengler J, Klugmann M, de la Rosa M, Wu W, Wang Q, Wei H, Moore AR, Roberts SA, Booth CJ, Hoellriegl W, Li D, Konkle B, Miao C, Reipert BM, Scheiflinger F, Rottensteiner H, Xiao W. Cao W, et al. Among authors: de la rosa m. Mol Ther Methods Clin Dev. 2020 Oct 22;19:486-495. doi: 10.1016/j.omtm.2020.10.013. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33313336 Free PMC article.
The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?
Lubich C, Allacher P, de la Rosa M, Bauer A, Prenninger T, Horling FM, Siekmann J, Oldenburg J, Scheiflinger F, Reipert BM. Lubich C, et al. Among authors: de la rosa m. Pharm Res. 2016 Sep;33(9):2239-49. doi: 10.1007/s11095-016-1961-x. Epub 2016 Jun 7. Pharm Res. 2016. PMID: 27271335
CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice.
Steinitz KN, van Helden PM, Binder B, Wraith DC, Unterthurner S, Hermann C, Schuster M, Ahmad RU, Weiller M, Lubich C, de la Rosa M, Schwarz HP, Reipert BM. Steinitz KN, et al. Among authors: de la rosa m. Blood. 2012 Apr 26;119(17):4073-82. doi: 10.1182/blood-2011-08-374645. Epub 2012 Mar 6. Blood. 2012. PMID: 22394599 Free PMC article.
IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells.
Brandenburg S, Takahashi T, de la Rosa M, Janke M, Karsten G, Muzzulini T, Orinska Z, Bulfone-Paus S, Scheffold A. Brandenburg S, et al. Among authors: de la rosa m. Eur J Immunol. 2008 Jun;38(6):1643-53. doi: 10.1002/eji.200737791. Eur J Immunol. 2008. PMID: 18493984 Free article.
486 results