Auburger GWJ - Search Results

1

The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene Expression.

Hansen M, Zeddies S, Meinders M, di Summa F, van Alphen FPJ, Hoogendijk AJ, Moore KS, Halbach M, Gutiérrez L, van den Biggelaar M, Thijssen-Timmer DC, Auburger GWJ, van den Akker E, von Lindern M, Rollmann E. Hansen M, et al. Among authors: auburger gwj. Int J Mol Sci. 2020 Jan 31;21(3):967. doi: 10.3390/ijms21030967. Int J Mol Sci. 2020. PMID: 32024018 Free PMC article.

2

Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.

Fittschen M, Lastres-Becker I, Halbach MV, Damrath E, Gispert S, Azizov M, Walter M, Müller S, Auburger G. Fittschen M, et al. Neurogenetics. 2015 Jul;16(3):181-92. doi: 10.1007/s10048-015-0441-5. Epub 2015 Feb 27. Neurogenetics. 2015. PMID: 25721894 Free PMC article.

3

Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.

Halbach MV, Stehning T, Damrath E, Jendrach M, Şen NE, Başak AN, Auburger G. Halbach MV, et al. PLoS One. 2015 Mar 19;10(3):e0121089. doi: 10.1371/journal.pone.0121089. eCollection 2015. PLoS One. 2015. PMID: 25790475 Free PMC article.

4

Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.

Meierhofer D, Halbach M, Şen NE, Gispert S, Auburger G. Meierhofer D, et al. Mol Cell Proteomics. 2016 May;15(5):1728-39. doi: 10.1074/mcp.M115.056770. Epub 2016 Feb 5. Mol Cell Proteomics. 2016. PMID: 26850065 Free PMC article.

5

Atxn2 Knockout and CAG42-Knock-in Cerebellum Shows Similarly Dysregulated Expression in Calcium Homeostasis Pathway.

Halbach MV, Gispert S, Stehning T, Damrath E, Walter M, Auburger G. Halbach MV, et al. Cerebellum. 2017 Feb;16(1):68-81. doi: 10.1007/s12311-016-0762-4. Cerebellum. 2017. PMID: 26868665 Free PMC article.

6

Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.

Sen NE, Canet-Pons J, Halbach MV, Arsovic A, Pilatus U, Chae WH, Kaya ZE, Seidel K, Rollmann E, Mittelbronn M, Meierhofer D, De Zeeuw CI, Bosman LWJ, Gispert S, Auburger G. Sen NE, et al. Neurobiol Dis. 2019 Dec;132:104559. doi: 10.1016/j.nbd.2019.104559. Epub 2019 Jul 31. Neurobiol Dis. 2019. PMID: 31376479 Free article.

7

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.

Sen NE, Arsovic A, Meierhofer D, Brodesser S, Oberschmidt C, Canet-Pons J, Kaya ZE, Halbach MV, Gispert S, Sandhoff K, Auburger G. Sen NE, et al. Int J Mol Sci. 2019 Nov 21;20(23):5854. doi: 10.3390/ijms20235854. Int J Mol Sci. 2019. PMID: 31766565 Free PMC article.

8

Mid-Gestation lethality of Atxn2l-Ablated Mice.

Key J, Harter PN, Sen NE, Gradhand E, Auburger G, Gispert S. Key J, et al. Int J Mol Sci. 2020 Jul 20;21(14):5124. doi: 10.3390/ijms21145124. Int J Mol Sci. 2020. PMID: 32698485 Free PMC article.

9

Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.

Arsović A, Halbach MV, Canet-Pons J, Esen-Sehir D, Döring C, Freudenberg F, Czechowska N, Seidel K, Baader SL, Gispert S, Sen NE, Auburger G. Arsović A, et al. Int J Mol Sci. 2020 Sep 12;21(18):6673. doi: 10.3390/ijms21186673. Int J Mol Sci. 2020. PMID: 32932600 Free PMC article.

10

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.

Canet-Pons J, Sen NE, Arsović A, Almaguer-Mederos LE, Halbach MV, Key J, Döring C, Kerksiek A, Picchiarelli G, Cassel R, René F, Dieterlé S, Fuchs NV, König R, Dupuis L, Lütjohann D, Gispert S, Auburger G. Canet-Pons J, et al. Neurobiol Dis. 2021 May;152:105289. doi: 10.1016/j.nbd.2021.105289. Epub 2021 Feb 10. Neurobiol Dis. 2021. PMID: 33577922 Free article.

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