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The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene Expression.
Hansen M, Zeddies S, Meinders M, di Summa F, van Alphen FPJ, Hoogendijk AJ, Moore KS, Halbach M, Gutiérrez L, van den Biggelaar M, Thijssen-Timmer DC, Auburger GWJ, van den Akker E, von Lindern M, Rollmann E. Hansen M, et al. Among authors: van den biggelaar m, van den akker e, van alphen fpj. Int J Mol Sci. 2020 Jan 31;21(3):967. doi: 10.3390/ijms21030967. Int J Mol Sci. 2020. PMID: 32024018 Free PMC article.
Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components.
Gazendam RP, van de Geer A, van Hamme JL, Tool AT, van Rees DJ, Aarts CE, van den Biggelaar M, van Alphen F, Verkuijlen P, Meijer AB, Janssen H, Roos D, van den Berg TK, Kuijpers TW. Gazendam RP, et al. Among authors: van den biggelaar m, van den berg tk, van rees dj, van hamme jl, van de geer a, van alphen f. Haematologica. 2016 May;101(5):587-96. doi: 10.3324/haematol.2015.136630. Epub 2016 Jan 22. Haematologica. 2016. PMID: 26802050 Free PMC article.
Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.
van den Eshof BL, Hoogendijk AJ, Simpson PJ, van Alphen FPJ, Zanivan S, Mertens K, Meijer AB, van den Biggelaar M. van den Eshof BL, et al. Among authors: van den biggelaar m, van alphen fpj. Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1891-1902. doi: 10.1161/ATVBAHA.117.309926. Epub 2017 Aug 17. Arterioscler Thromb Vasc Biol. 2017. PMID: 28818855 Free article.
Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages.
Heideveld E, Hampton-O'Neil LA, Cross SJ, van Alphen FPJ, van den Biggelaar M, Toye AM, van den Akker E. Heideveld E, et al. Among authors: van den biggelaar m, van den akker e, van alphen fpj. Haematologica. 2018 Mar;103(3):395-405. doi: 10.3324/haematol.2017.179341. Epub 2017 Dec 28. Haematologica. 2018. PMID: 29284682 Free PMC article.
Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells.
Salerno F, Engels S, van den Biggelaar M, van Alphen FPJ, Guislain A, Zhao W, Hodge DL, Bell SE, Medema JP, von Lindern M, Turner M, Young HA, Wolkers MC. Salerno F, et al. Among authors: van den biggelaar m, van alphen fpj. Nat Immunol. 2018 Aug;19(8):828-837. doi: 10.1038/s41590-018-0155-6. Epub 2018 Jul 9. Nat Immunol. 2018. PMID: 29988089 Free PMC article.
Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.
Karampini E, Schillemans M, Hofman M, van Alphen F, de Boer M, Kuijpers TW, van den Biggelaar M, Voorberg J, Bierings R. Karampini E, et al. Among authors: van den biggelaar m, van alphen f. Haematologica. 2019 Oct;104(10):2091-2099. doi: 10.3324/haematol.2018.207787. Epub 2019 Jan 10. Haematologica. 2019. PMID: 30630984 Free PMC article.
Alternative trafficking of Weibel-Palade body proteins in CRISPR/Cas9-engineered von Willebrand factor-deficient blood outgrowth endothelial cells.
Schillemans M, Kat M, Westeneng J, Gangaev A, Hofman M, Nota B, van Alphen FPJ, de Boer M, van den Biggelaar M, Margadant C, Voorberg J, Bierings R. Schillemans M, et al. Among authors: van den biggelaar m, van alphen fpj. Res Pract Thromb Haemost. 2019 Aug 1;3(4):718-732. doi: 10.1002/rth2.12242. eCollection 2019 Oct. Res Pract Thromb Haemost. 2019. PMID: 31624792 Free PMC article.
CD29 identifies IFN-γ-producing human CD8+ T cells with an increased cytotoxic potential.
Nicolet BP, Guislain A, van Alphen FPJ, Gomez-Eerland R, Schumacher TNM, van den Biggelaar M, Wolkers MC. Nicolet BP, et al. Among authors: van den biggelaar m, van alphen fpj. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6686-6696. doi: 10.1073/pnas.1913940117. Epub 2020 Mar 11. Proc Natl Acad Sci U S A. 2020. PMID: 32161126 Free PMC article.
69 results