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RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness.
Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG; PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. Novak T, et al. Among authors: mcdonald dr. J Allergy Clin Immunol. 2020 Jun;145(6):1673-1680.e11. doi: 10.1016/j.jaci.2020.01.040. Epub 2020 Feb 6. J Allergy Clin Immunol. 2020. PMID: 32035159 Free PMC article.
Immune deficiency caused by impaired expression of nuclear factor-kappaB essential modifier (NEMO) because of a mutation in the 5' untranslated region of the NEMO gene.
Mooster JL, Cancrini C, Simonetti A, Rossi P, Di Matteo G, Romiti ML, Di Cesare S, Notarangelo L, Geha RS, McDonald DR. Mooster JL, et al. Among authors: mcdonald dr. J Allergy Clin Immunol. 2010 Jul;126(1):127-32.e7. doi: 10.1016/j.jaci.2010.04.026. Epub 2010 Jun 12. J Allergy Clin Immunol. 2010. PMID: 20542322 Free PMC article.
Immune dysregulation and multisystem inflammatory syndrome in children (MIS-C) in individuals with haploinsufficiency of SOCS1.
Lee PY, Platt CD, Weeks S, Grace RF, Maher G, Gauthier K, Devana S, Vitali S, Randolph AG, McDonald DR, Geha RS, Chou J. Lee PY, et al. Among authors: mcdonald dr. J Allergy Clin Immunol. 2020 Nov;146(5):1194-1200.e1. doi: 10.1016/j.jaci.2020.07.033. Epub 2020 Aug 25. J Allergy Clin Immunol. 2020. PMID: 32853638 Free PMC article.
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.
Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, Al-Herz W, Barlan I, Baris S, Kutukculer N, Ochs HD, Plebani A, Kanariou M, Lefranc G, Reisli I, Fitzgerald KA, Golenbock D, Manis J, Keles S, Ceja R, Chatila TA, Geha RS. Jabara HH, et al. Among authors: mcdonald dr. Nat Immunol. 2012 May 13;13(6):612-20. doi: 10.1038/ni.2305. Nat Immunol. 2012. PMID: 22581261 Free PMC article.
43 results