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PCSK9 Inhibitors: From Nature's Lessons to Clinical Utility.
Raal FJ, Chilton R, Ranjith N, Rambiritch V, Leisegang RF, Ebrahim IO, Tonder AV, Shunmoogam N, Bouharati C, Musa MG, Karamchand S, Naidoo P, Blom DJ. Raal FJ, et al. Endocr Metab Immune Disord Drug Targets. 2020;20(6):840-854. doi: 10.2174/1871530320666200213114138. Endocr Metab Immune Disord Drug Targets. 2020. PMID: 32053090 Review.
Discovering familial hypercholesterolaemia.
Blom DJ, Raal FJ, Marais AD. Blom DJ, et al. Among authors: raal fj. S Afr Med J. 2008 Apr;98(4):232. S Afr Med J. 2008. PMID: 18642461 No abstract available.
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial.
Raal FJ, Santos RD, Blom DJ, Marais AD, Charng MJ, Cromwell WC, Lachmann RH, Gaudet D, Tan JL, Chasan-Taber S, Tribble DL, Flaim JD, Crooke ST. Raal FJ, et al. Lancet. 2010 Mar 20;375(9719):998-1006. doi: 10.1016/S0140-6736(10)60284-X. Lancet. 2010. PMID: 20227758 Clinical Trial.
Reduction in lipoprotein(a) with PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of more than 1,300 patients in 4 phase II trials.
Raal FJ, Giugliano RP, Sabatine MS, Koren MJ, Langslet G, Bays H, Blom D, Eriksson M, Dent R, Wasserman SM, Huang F, Xue A, Albizem M, Scott R, Stein EA. Raal FJ, et al. J Am Coll Cardiol. 2014 Apr 8;63(13):1278-1288. doi: 10.1016/j.jacc.2014.01.006. Epub 2014 Feb 5. J Am Coll Cardiol. 2014. PMID: 24509273 Free article. Clinical Trial.
219 results